
Concept explainers
(a)
To determine: The cell junction which stops the movement of particles between cells.
Introduction: Cell junctions are responsible for binds the cells to form tissues. These junctions can be formed between cells or between cell and matrix. Occluding junctions are one of the strong cell junctions present in tissues. These are also called tight junctions in vertebrates.
(b)
To determine: The cell junction which permits the direct movement of materials between the cytoplasm of neighboring cells.
Introduction: Cell junctions are formed between the cell or between the cell and extracellular matrix during the development period of a tissue. One of the strong cell junctions formed is communicating junction. This junction is responsible for interaction between cells and is termed as gap junctions in animals.
(c)
To determine: The cell junction which provides the strongest cell-cell adhesion.
Introduction: Anchoring junctions are the cell junctions which provide support to the tissue. These junctions create linkages between one cell and another cell or form cell-matrix adhesion. Cadherins are responsible for cell-cell adhesions whereas integrins are responsible for cell-matrix adhesions.
(d)
To determine: The cell junctions which connects actin fibers present in the cell to the extracellular matrix
Introduction: Cell junctions are formed during the development phase of a tissue. Anchoring junctions are one of the cell junctions formed in tissue. They provide mechanical strength to the tissue. These junctions connect one cell to another or cell with the extracellular matrix.

Want to see the full answer?
Check out a sample textbook solution
Chapter 3 Solutions
Human Physiology: An Integrated Approach (8th Edition)
- You intend to insert patched dominant negative DNA into the left half of the neural tube of a chick. 1) Which side of the neural tube would you put the positive electrode to ensure that the DNA ends up on the left side? 2) What would be the internal (within the embryo) control for this experiment? 3) How can you be sure that the electroporation method itself is not impacting the embryo? 4) What would you do to ensure that the electroporation is working? How can you tell?arrow_forwardDescribe a method to document the diffusion path and gradient of Sonic Hedgehog through the chicken embryo. If modifying the protein, what is one thing you have to consider in regards to maintaining the protein’s function?arrow_forwardThe following table is from Kumar et. al. Highly Selective Dopamine D3 Receptor (DR) Antagonists and Partial Agonists Based on Eticlopride and the D3R Crystal Structure: New Leads for Opioid Dependence Treatment. J. Med Chem 2016.arrow_forward
- The following figure is from Caterina et al. The capsaicin receptor: a heat activated ion channel in the pain pathway. Nature, 1997. Black boxes indicate capsaicin, white circles indicate resinferatoxin. You are a chef in a fancy new science-themed restaurant. You have a recipe that calls for 1 teaspoon of resinferatoxin, but you feel uncomfortable serving foods with "toxins" in them. How much capsaicin could you substitute instead?arrow_forwardWhat protein is necessary for packaging acetylcholine into synaptic vesicles?arrow_forward1. Match each vocabulary term to its best descriptor A. affinity B. efficacy C. inert D. mimic E. how drugs move through body F. how drugs bind Kd Bmax Agonist Antagonist Pharmacokinetics Pharmacodynamicsarrow_forward
- 50 mg dose of a drug is given orally to a patient. The bioavailability of the drug is 0.2. What is the volume of distribution of the drug if the plasma concentration is 1 mg/L? Be sure to provide units.arrow_forwardDetermine Kd and Bmax from the following Scatchard plot. Make sure to include units.arrow_forwardChoose a catecholamine neurotransmitter and describe/draw the components of the synapse important for its signaling including synthesis, packaging into vesicles, receptors, transporters/degradative enzymes. Describe 2 drugs that can act on this system.arrow_forward
- The following figure is from Caterina et al. The capsaicin receptor: a heat activated ion channel in the pain pathway. Nature, 1997. Black boxes indicate capsaicin, white circles indicate resinferatoxin. a) Which has a higher potency? b) Which is has a higher efficacy? c) What is the approximate Kd of capsaicin in uM? (you can round to the nearest power of 10)arrow_forwardWhat is the rate-limiting-step for serotonin synthesis?arrow_forwardWhat enzyme is necessary for synthesis of all of the monoamines?arrow_forward
- Human Physiology: From Cells to Systems (MindTap ...BiologyISBN:9781285866932Author:Lauralee SherwoodPublisher:Cengage LearningConcepts of BiologyBiologyISBN:9781938168116Author:Samantha Fowler, Rebecca Roush, James WisePublisher:OpenStax CollegeBiology (MindTap Course List)BiologyISBN:9781337392938Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. BergPublisher:Cengage Learning
- Human Biology (MindTap Course List)BiologyISBN:9781305112100Author:Cecie Starr, Beverly McMillanPublisher:Cengage LearningHuman Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage LearningBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax





