The correct arrangement of compartments, such as interstitial fluid, plasma, and intracellular fluid with respect to the movement of a glucose molecule in the body. Introduction: Small intestine is the part of the gastrointestinal tract where the majority of biomolecules are digested and absorbed into the body. The transportation of these absorbed nutrients is carried out with the help of blood.

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Answer 1

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Chapter 3, Problem 22RQ

Summary Introduction

To determine: The correct arrangement of compartments, such as interstitial fluid, plasma, and intracellular fluid with respect to the movement of a glucose molecule in the body.

Introduction: Small intestine is the part of the gastrointestinal tract where the majority of biomolecules are digested and absorbed into the body. The transportation of these absorbed nutrients is carried out with the help of blood.

Summary Introduction

To determine: The compartments out of interstitial fluid, intracellular fluid and plasma which are considered as extracellular fluid (ECF).

Introduction: The substances synthesized and secreted by the cells forms the extracellular matrix. This matrix consists of extracellular fluid in which cells and other substances are suspended. Plasma is the extracellular fluid present in blood vessels in which blood cells are suspended.

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Kinetics: One-Compartment First-Order Absorption 1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple routes of administration provides greater insight than a single route of administration alone. The following data was collected in 250-g rats following bolus IV, oral (PO), and intraperitoneal (ip) administration. Using this data and set of graphs, determine:(calculate for each variable) (a) k, C0, V, and AUC* for the bolus iv data (b) k, ka, B1, and AUC* for the po data c) k, ka, B1, and AUC* for the ip data (d) relative bioavailability for po vs ip, Fpo/Fip (e)absolute ip bioavailability, Fip (f) absolute po bioavailability, Fpo

3. A promising new drug is being evaluated in human trials. Based on preliminary human tests, this drug is most effective when plasma levels exceed 30 mg/L. Measurements from preliminary tests indicate the following human pharmacokinetic parameter values: t1/2,elim = 4.6hr, t1/2,abs = 0.34hr, VD = 0.29 L/kg, Foral = 72%. Based on these parameters, estimate the following if a 49 kg woman were to receive a 1000mg oral dose of this drug: (a) Estimate the plasma concentration of the drug at 1hr, 6 hr, and 20hr after taking the drug ( Concentration estimate) (b) Estimate the time for maximum plasma concentration (tmax). (c) Estimate the maximum plasma concentration (Cmax). (d) Estimate the time at which the plasma level first rises above 30 mg/L. (Note this is a trial and error problem where you must guess a time, plug it into the concentration equation, and determine if it is close to 30 mg/L. Hint: based on part (a) it should be apparent that the answer is less than 1hr.) (e)…

List substitutions in your diet you could make to improve it based on what you know now about a balanced diet. For instance, if you like to drink soda, you might substitute skim milk or water for some of the soft drinks you consumed. List the item you wish to replace with the new item and what you hope to accomplish with that substitution. Be sure to choose foods you know that you'd enjoy and you consider more "healthful." If you feel your diet is already balanced, describe how you accomplish your balanced intake and when you began eating this way.

Answer 2

Question

Chapter 3, Problem 22RQ

Summary Introduction

To determine: The correct arrangement of compartments, such as interstitial fluid, plasma, and intracellular fluid with respect to the movement of a glucose molecule in the body.

Introduction: Small intestine is the part of the gastrointestinal tract where the majority of biomolecules are digested and absorbed into the body. The transportation of these absorbed nutrients is carried out with the help of blood.

Summary Introduction

To determine: The compartments out of interstitial fluid, intracellular fluid and plasma which are considered as extracellular fluid (ECF).

Introduction: The substances synthesized and secreted by the cells forms the extracellular matrix. This matrix consists of extracellular fluid in which cells and other substances are suspended. Plasma is the extracellular fluid present in blood vessels in which blood cells are suspended.

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Answer 3

Question

Chapter 3, Problem 22RQ

Summary Introduction

To determine: The correct arrangement of compartments, such as interstitial fluid, plasma, and intracellular fluid with respect to the movement of a glucose molecule in the body.

Introduction: Small intestine is the part of the gastrointestinal tract where the majority of biomolecules are digested and absorbed into the body. The transportation of these absorbed nutrients is carried out with the help of blood.

Summary Introduction

To determine: The compartments out of interstitial fluid, intracellular fluid and plasma which are considered as extracellular fluid (ECF).

Introduction: The substances synthesized and secreted by the cells forms the extracellular matrix. This matrix consists of extracellular fluid in which cells and other substances are suspended. Plasma is the extracellular fluid present in blood vessels in which blood cells are suspended.

Expert Solution & Answer

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Answer 4

Question

Chapter 3, Problem 22RQ

Summary Introduction

To determine: The correct arrangement of compartments, such as interstitial fluid, plasma, and intracellular fluid with respect to the movement of a glucose molecule in the body.

Introduction: Small intestine is the part of the gastrointestinal tract where the majority of biomolecules are digested and absorbed into the body. The transportation of these absorbed nutrients is carried out with the help of blood.

Summary Introduction

To determine: The compartments out of interstitial fluid, intracellular fluid and plasma which are considered as extracellular fluid (ECF).

Introduction: The substances synthesized and secreted by the cells forms the extracellular matrix. This matrix consists of extracellular fluid in which cells and other substances are suspended. Plasma is the extracellular fluid present in blood vessels in which blood cells are suspended.

Expert Solution & Answer

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Answer 5

Chapter 3, Problem 22RQ

Summary Introduction

To determine: The correct arrangement of compartments, such as interstitial fluid, plasma, and intracellular fluid with respect to the movement of a glucose molecule in the body.

Introduction: Small intestine is the part of the gastrointestinal tract where the majority of biomolecules are digested and absorbed into the body. The transportation of these absorbed nutrients is carried out with the help of blood.

Summary Introduction

To determine: The compartments out of interstitial fluid, intracellular fluid and plasma which are considered as extracellular fluid (ECF).

Introduction: The substances synthesized and secreted by the cells forms the extracellular matrix. This matrix consists of extracellular fluid in which cells and other substances are suspended. Plasma is the extracellular fluid present in blood vessels in which blood cells are suspended.

Answer 6

Chapter 3, Problem 22RQ

Summary Introduction

To determine: The correct arrangement of compartments, such as interstitial fluid, plasma, and intracellular fluid with respect to the movement of a glucose molecule in the body.

Introduction: Small intestine is the part of the gastrointestinal tract where the majority of biomolecules are digested and absorbed into the body. The transportation of these absorbed nutrients is carried out with the help of blood.

Answer 7

Chapter 3, Problem 22RQ

Summary Introduction

To determine: The correct arrangement of compartments, such as interstitial fluid, plasma, and intracellular fluid with respect to the movement of a glucose molecule in the body.

Introduction: Small intestine is the part of the gastrointestinal tract where the majority of biomolecules are digested and absorbed into the body. The transportation of these absorbed nutrients is carried out with the help of blood.

Answer 8

Summary Introduction

To determine: The compartments out of interstitial fluid, intracellular fluid and plasma which are considered as extracellular fluid (ECF).

Introduction: The substances synthesized and secreted by the cells forms the extracellular matrix. This matrix consists of extracellular fluid in which cells and other substances are suspended. Plasma is the extracellular fluid present in blood vessels in which blood cells are suspended.

Answer 9

Summary Introduction

To determine: The compartments out of interstitial fluid, intracellular fluid and plasma which are considered as extracellular fluid (ECF).

Introduction: The substances synthesized and secreted by the cells forms the extracellular matrix. This matrix consists of extracellular fluid in which cells and other substances are suspended. Plasma is the extracellular fluid present in blood vessels in which blood cells are suspended.

Answer 10

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Answer 13

Ch. 3.2 - Name three types of lipids found in cell...Ch. 3.2 - Describe three types of membrane proteins and how...Ch. 3.2 - Why do phospholipids in cell membranes form a...Ch. 3.2 - How many phospholipid bilayers will a substance...Ch. 3.3 - Name the three sizes of cytoplasmic protein...Ch. 3.3 - How would the absence of a flagellum affect a...Ch. 3.3 - Prob. 7CC Ch. 3.3 - Prob. 8CC Ch. 3.3 - What is the function of motor proteins?Ch. 3.3 - What distinguishes organelles from inclusions?

Solution Summary: The author explains that the correct arrangement of compartments with respect to the movement of a glucose molecule in the body is intracellular fluid, interstitial fluid and plasma.

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