Chapter 3.3, Problem 1QTC

Summary Introduction

To review:

The electron microscope is an advanced and very powerful tool used for visualizing biological samples. Through the electron microscope, scientists are able to view the intracellular structure of cells, tissues, and small organisms in detail, whenever, these biological samples can’t be viewed under inverted and scanning microscopes.

Introduction:

The samples preparation for visualization is a complex process. During preparation process, the tissue or are damaged and causes changes in the sample’s appearance’s thus the artefacts present in many ways such as here loss of continuity in the membranes, distortion or disorganisation of organelles, empty spaces in the cytoplasm of cells or sharp bends or curves in filamentous structures that are usually straight, such as microtubules and so on. Thus, microscopists recognize the difference between an artifact and true structure by comparing at the same or similar specimens