HUMAN BIOLOGY W/ACCESS
16th Edition
ISBN: 9781260997231
Author: Mader
Publisher: MCG
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Chapter 3.3, Problem 1CYP
Summarize how the fluid-mosaic model describes the structure of the plasma membrane.
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. Consider a base substitution mutation that occurred in a DNA sequence that resulted in a change in the
encoded protein from the amino acid glutamic acid to aspartic acid. Normally the glutamic acid amino acid
is located on the outside of the soluble protein but not near an active site.
O-H¨
A. What type of mutation occurred?
O-H
B. What 2 types of chemical bonds are found in the R-groups
of each amino acid? The R groups are shaded.
CH2
CH2
CH2
H2N-C-COOH
H2N-C-COOH
1
H
Glutamic acid
H
Aspartic acid
C. What 2 types of bonds could each R-group of each of these amino acids form with other molecules?
D. Consider the chemical properties of the two amino acids and the location of the amino acid in the
protein. Explain what effect this mutation will have on this protein's function and why.
engineered constructs that consist of hollow fibers are acting as synthetic capillaries, around which cells have been loaded. The cellular space around a single fiber can be modeled as if it were a Krogh tissue cylinder. Each fiber has an outside “capillary” radius of 100 µm and the “tissue” radius can be taken as 200 µm. The following values apply to the device:R0 = 20 µM/secaO2 = 1.35 µM/mmHgDO2,T = 1.67 x 10-5 cm2/secPO2,m = 4 x 10-3 cm/secInstead of blood inside the fibers, the oxygen transport and tissue consumption are being investigated by usingan aqueous solution saturated with pure oxygen. As a result, there is no mass transfer resistance in the synthetic“capillary”, only that due to the membrane itself. Rather than accounting for pO2 variations along the length ofthe fiber, use an average value in the “capillary” of 130 mmHg.Is the tissue fully oxygenated?
Molecular Biology
Please help with question. thank you
You are studying the expression of the lac operon. You have isolated mutants as described below. In the presence of glucose, explain/describe what would happen, for each mutant, to the expression of the lac operon when you add lactose AND what would happen when the bacteria has used up all of the lactose (if the mutant is able to use lactose).5. Mutations in the lac operator that strengthen the binding of the lac repressor 200 fold
6. Mutations in the promoter that prevent binding of RNA polymerase
7. Mutations in CRP/CAP protein that prevent binding of cAMP8. Mutations in sigma factor that prevent binding of sigma to core RNA polymerase
Chapter 3 Solutions
HUMAN BIOLOGY W/ACCESS
Ch. 3.1 - State the basic principles of the cell theory.Ch. 3.1 - Prob. 2LOCh. 3.1 - Prob. 3LOCh. 3.1 - Discuss how a researcher might use a GFP-labeled...Ch. 3.1 - How might a meal of a cheeseburger and fries be...Ch. 3.1 - Summarize the cell theory and state its importance...Ch. 3.1 - Prob. 2CYPCh. 3.1 - Prob. 3CYPCh. 3.2 - Distinguish between the structure of a prokaryotic...Ch. 3.2 - Identify the role of the plasma membrane and...
Ch. 3.2 - Summarize how eukaryotic cells evolved from...Ch. 3.2 - Summarize the role of the plasma membrane in a...Ch. 3.2 - Describe the main differences between a eukaryotic...Ch. 3.2 - Describe the possible evolution of the nucleus,...Ch. 3.3 - Prob. 1LOCh. 3.3 - Prob. 2LOCh. 3.3 - Explain how tonicity relates to the direction of...Ch. 3.3 - Compare passive-transport and active-transport...Ch. 3.3 - Summarize how eukaryotic cells move large...Ch. 3.3 - Summarize how the fluid-mosaic model describes the...Ch. 3.3 - Prob. 2CYPCh. 3.3 - Prob. 3CYPCh. 3.4 - Describe the structure of the nucleus and explain...Ch. 3.4 - Summarize the function of the organelles of the...Ch. 3.4 - 3. Explain the role and location of the...Ch. 3.4 - Prob. 1CYPCh. 3.4 - Explain how the nucleus, ribosomes, and rough...Ch. 3.4 - Prob. 3CYPCh. 3.5 - Prob. 1LOCh. 3.5 - Summarize the major protein fibers In the...Ch. 3.5 - Prob. 3LOCh. 3.5 - Prob. 4LOCh. 3.5 - Prob. 1CYPCh. 3.5 - Prob. 2CYPCh. 3.5 - Prob. 3CYPCh. 3.6 - Prob. 1LOCh. 3.6 - Prob. 2LOCh. 3.6 - Summarize the roles of the anaerobic and aerobic...Ch. 3.6 - Prob. 4LOCh. 3.6 - How might a meal of a cheeseburger and fries be...Ch. 3.6 - Even though Figure 3B does not indicate the need...Ch. 3.6 - Summarize the roles of enzymes in chemical...Ch. 3.6 - Prob. 2CYPCh. 3.6 - Explain why the ATP cycle resembles that of a...Ch. 3.6 - Prob. 4CYPCh. 3 - Prob. 1ACh. 3 - The cell theory states that all life comes from...Ch. 3 - Prob. 3ACh. 3 - 4.The endosymbiotic theory explains which of the...Ch. 3 - Which of the following is not part of the...Ch. 3 - Prob. 6ACh. 3 - Prob. 7ACh. 3 - Prob. 8ACh. 3 - Prob. 9ACh. 3 - Prob. 10ACh. 3 - Prob. 11ACh. 3 - Prob. 12ACh. 3 - The cytoskeleton of a cell consists of all of the...Ch. 3 - Prob. 14ACh. 3 - Prob. 15ACh. 3 - Prob. 16ACh. 3 - Prob. 17ACh. 3 - Prob. 18ACh. 3 - Prob. 1TCCh. 3 - Prob. 2TCCh. 3 - Prob. 3TC
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