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The results of the HIV (human immunodeficiency virus) experiment and compare them with the Ebola virus (EBOV) experiment.
Introduction:
Ebola virus can lead to severe and fatal hemorrhagic fever in the human beings. The disease caused is known as Ebola virus disease. HIV is the subgroup of retrovirus (lentivirus) that leads to AIDS (acquired immunodeficiency syndrome). HIV utilizes CD4 (cluster of differentiation 4) receptor in order to enter the T helper cells. The cells that have free and unbound CD4 on their surface will be infected by the HIV. CD4 is a membrane protein that HIV utilizes to enter the cells. Similarly, researchers have identified many surface proteins that may work as a virus receptor for the EBOV. The figure below shows the experiment that was performed using HIV virus.
Experiment: One hundred sixty identical samples of T helper cells were grown in the culture. Different antibodies were then added into each sample of the cells. The antibody inhibits the specific membrane protein. A constant number of virions were then added to the samples followed by the incubation process under the conditions that are optimal for the viruses to enter.
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Chapter 33 Solutions
Biological Science (6th Edition)
- O Macmillan Learning Glu-His-Trp-Ser-Gly-Leu-Arg-Pro-Gly The pKa values for the peptide's side chains, terminal amino groups, and carboxyl groups are provided in the table. Amino acid Amino pKa Carboxyl pKa Side-chain pKa glutamate 9.60 2.34 histidine 9.17 1.82 4.25 6.00 tryptophan 9.39 2.38 serine 9.15 2.21 glycine 9.60 2.34 leucine 9.60 2.36 arginine 9.04 2.17 12.48 proline 10.96 1.99 Calculate the net charge of the molecule at pH 3. net charge at pH 3: Calculate the net charge of the molecule at pH 8. net charge at pH 8: Calculate the net charge of the molecule at pH 11. net charge at pH 11: Estimate the isoelectric point (pl) for this peptide. pl:arrow_forwardBiology Questionarrow_forwardThis entire structure (Pinus pollen cone) using lifecycle terminology is called what?arrow_forward
- This entire structure using lifecycle terminology is called what? megastrobilus microstrobilus megasporophyll microsporophyll microsporangium megasporangium none of thesearrow_forwardHow much protein should Sarah add to her diet if she gets pregnant? Sarah's protein requirements during pregnancy would be higher. See Hint B2. During calculations, use numbers rounded to the first decimal place. In your answer, round the number of grams to the nearest whole number. _______ g ?arrow_forwardC MasteringHealth MasteringNu X session.healthandnutrition-mastering.pearson.com/myct/itemView?assignment ProblemID=17396422&attemptNo=1&offset=prevarrow_forwardMost people, even those who exercise regularly at low to average intensity (1 hour at the gym or a 2- to 3-mile walk several times per week), do not need an increased protein intake. What would be the protein needs of a man named Josh who exercises moderately and is the same age and size as Wayne? Josh is 5 ft, 8 in tall and weighs 183 lb. Round the number of grams to the nearest whole number. During calculations, use numbers rounded to the first decimal place. Because protein requirement is a range, please enter two numbers: lower and upper range values, respectively. Separate the lower and upper range values, in that order, by a comma. ___, ___ g ?arrow_forwardC MasteringHealth MasteringNu X session.healthandnutrition-mastering.pearson.com/myct/itemView?assignment ProblemID=17396422&attemptNo=1&offset=prevarrow_forwardIf left untreated, most HIV-infected individuals will develop AIDS. Current treatments are focused on highlyactive antiretroviral therapy (HAART). HAART usually consists of an orally delivered drug cocktail containingtwo different reverse transcriptase inhibitors and one other drug, such as a protease inhibitor. Question: Develop a pharmacokinetic model of HAART treatment. Consider all 3 drugs. Make sure to include adiagram that illustrates your thinking, state all assumptions, and define your variables. Whatparameters would you need to know to find the concentration of drug in the plasma? In the T cells?(You do not need to write out or solve any equations.)arrow_forwardnot use ai pleseaarrow_forward(A) 25 20 20 15 NPP (Mg C/ha/yr) 10 10 5 0 0 2,000 4,000 6,000 ECOLOGY 4e, Figure 20.11 (Part 1) 2017 Sinauer Associates, Inc. Average annual precipitation (mm) 8,000arrow_forwardexplain the cascade of events (starting with relaxing trade winds) that occurs during El Niño in the eastern Pacific (off the coasts of California/North America and Peru/South America) and which lead to food-chain collapse - start with changes in the physical/oceanographic conditions, andthen systematically describe the cascading effects at each level of the food chain -arrow_forwardarrow_back_iosSEE MORE QUESTIONSarrow_forward_iosRecommended textbooks for you
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