The mechanisms for the synthesis of c-AMP from ATP in the presence of adenylyl cyclise and for the dissociation of cAMP and 5’-AMP by phosphodiesterase needs to be determined. Concept Introduction: Cyclic adenosine monophosphate ( cAMP ) is known to be a second messenger used for the intracellular signal induction. It is produced from adenosine triphosphate ( ATP ) in the presence of enzymes (g-proteins) attached to the metabotropic receptors. It releases the cAMP after the activation of the receptor. It is important in all the main biological processes. It is mainly used for transfer of signal in between the cells of different organisms.

Question

Obtain the sequence for the 5-HT receptor HTR1A and generate a hydropathy plot usingthe ExPASY tool ProtScale, the appropriate window, and the Kyte-Doolittle weightingalgorithm. How many transmembrane domains are present in this receptor?

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Question

Chapter 32, Problem 12P

Interpretation Introduction

Interpretation:

The mechanisms for the synthesis of c-AMP from ATP in the presence of adenylyl cyclise and for the dissociation of cAMP and 5’-AMP by phosphodiesterase needs to be determined.

Concept Introduction:

Cyclic adenosine monophosphate (cAMP) is known to be a second messenger used for the intracellular signal induction. It is produced from adenosine triphosphate (ATP) in the presence of enzymes (g-proteins) attached to the metabotropic receptors. It releases the cAMP after the activation of the receptor.

It is important in all the main biological processes. It is mainly used for transfer of signal in between the cells of different organisms.

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