Brock Biology of Microorganisms (14th Edition)
Brock Biology of Microorganisms (14th Edition)
14th Edition
ISBN: 9780321897398
Author: Michael T. Madigan, John M. Martinko, Kelly S. Bender, Daniel H. Buckley, David A. Stahl, Thomas Brock
Publisher: PEARSON
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Chapter 30.3, Problem 2MQ
Summary Introduction

Rickettsias are small obligate intracellular parasites which get transmitted to the host with the help of vectors such as arthropods (examples are fleas, lice, or ticks). It is responsible for causing diseases like typhus, spotted fever, ehrlichiosis, and tick borne anaplasmosis Microorganisms like Rickettsia prowazekii, Rickettsia rickettsii and Ehrlichia chaffeensis are mainly responsible for causing such diseases.

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You aim to test the hypothesis that the Tbx4 and Tbx5 genes inhibit each other's expression during limb development. With access to chicken embryos and viruses capable of overexpressing Tbx4 and Tbx5, describe an experiment to investigate whether these genes suppress each other's expression in the limb buds. What results would you expect if they do repress each other? What results would you expect if they do not repress each other?
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