EBK ESSENTIALS OF BIOLOGY
EBK ESSENTIALS OF BIOLOGY
4th Edition
ISBN: 9780100237209
Author: Mader
Publisher: YUZU
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Chapter 30.2, Problem 4CYP

Contrast the environmental impact of an MDC with that of an LDC

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"One of the symmetry breaking events in mouse gastrulation requires the amplification of Nodal on the side of the embryo opposite to the Anterior Visceral Endoderm (AVE). Describe one way by which Nodal gets amplified in this region." My understanding of this is that there are a few ways nodal is amplified though I'm not sure if this is specifically occurs on the opposite side of the AVE.  1. pronodal cleaved by protease -> active nodal 2. Nodal -> BMP4 -> Wnt-> nodal 3. Nodal-> Nodal, Fox1 binding site  4. BMP4 on outside-> nodal  Are all of these occuring opposite to AVE?
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EBK ESSENTIALS OF BIOLOGY

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