BIOLOGY THE ESSENTIALS CONNECT ONLY
BIOLOGY THE ESSENTIALS CONNECT ONLY
3rd Edition
ISBN: 9781264735433
Author: Hoefnagels
Publisher: McGrawHill
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Chapter 30, Problem 2MCQ
Summary Introduction

Introduction:

Hormones are the chemical messengers that are secreted by the endocrine glands. These messengers control most of the body functions from simpler to complex ones. The circulatory system transports these hormones to the target cell.

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You aim to test the hypothesis that the Tbx4 and Tbx5 genes inhibit each other's expression during limb development. With access to chicken embryos and viruses capable of overexpressing Tbx4 and Tbx5, describe an experiment to investigate whether these genes suppress each other's expression in the limb buds. What results would you expect if they do repress each other? What results would you expect if they do not repress each other?
You decide to delete Fgf4 and Fgf8 specifically in the limb bud. Explain why you would not knock out these genes in the entire embryo instead.
You implant an FGF10-coated bead into the anterior flank of a chicken embryo, directly below the level of the wing bud. What is the phenotype of the resulting ectopic limb?  Briefly describe the expected expression domains of 1) Shh, 2) Tbx4, and 3) Tbx5 in the resulting ectopic limb bud.

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BIOLOGY THE ESSENTIALS CONNECT ONLY

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Great Glands - Your Endocrine System: CrashCourse Biology #33; Author: CrashCourse;https://www.youtube.com/watch?v=WVrlHH14q3o;License: Standard Youtube License