EBK BIOCHEMISTRY
6th Edition
ISBN: 9781337431200
Author: GRISHAM
Publisher: CENGAGE LEARNING - CONSIGNMENT
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Chapter 30, Problem 17P
Exploring the Structure of the 30S Ribosomal Subunit Go to www.pdh.org and bring up PDB file 1GIX, which shows the 30S ribosomal subunit, the three tRNAs, and mRNA. In the box on the right titled ‘Biological Assembly.� click “More Images.� and then scroll down to look at the Interactive Vic By moving your cursor over the image, you can rotate it to view it from any perspective.
a. How are the ribosomal proteins represented in the image?
b. How is the 16S rRNA portrayed?
c. Rotate the image to see how the tRNAs stick out from the structure. Which end of the tRNA is sticking out?
d. Where will these ends of the tRNAs lie when the 50S subunit binds to this complex?
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12. When glutamic acid is heated to 180°C., it loses a molecule of water to form a
lactam. The bond that creates the lactam is an amide bond that forms between the
amino nitrogen and the carbon of the side chain -COOH group. What is the most
reasonable structure for this lactam? (NOTE: The structure of glutamic acid is shown
in Question 1.)
COOH
COOH
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C
D
COOH
B
COOH
E
COOH
10. Which one of the
following compounds is
the major organic product
of the series of reactions
shown here?
Ph
A
OH
Ph
B
CO₂Et
Br
-H
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CO₂Et
1. NaOEt
1. NaOH, H₂O
2. H3O+
2. PhCH2CH2Br
3. heat
NH2
Ph
OH
NH2
0
OH
Ph
OH
NH2
Ph
D
NH2
E
OH
1. What is the isoelectric point of glutamic acid?
(Glutamic acid has pKa1 2.10, pKa2 4.07, pKaз 9.47)
A) pH 2.1
D) pH 6.8
B) pH 3.1
C) pH 4.1
E) pH 9.5
HO
NH2
Glutamic acid
(shown without charges)
OH
Chapter 30 Solutions
EBK BIOCHEMISTRY
Ch. 30 - Prob. 1PCh. 30 - Prob. 2PCh. 30 - The Second Genetic Code Review the evidence...Ch. 30 - Codon-Anticodon Recognition: Base-Pairing...Ch. 30 - Consequences of the Wobble Hypothesis Point out...Ch. 30 - Prob. 6PCh. 30 - Prob. 7PCh. 30 - Prob. 8PCh. 30 - Prob. 9PCh. 30 - The Consequences of Ribosome Complexity Eukaryotic...
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- f. The genetic code is given below, along with a short strand of template DNA. Write the protein segment that would form from this DNA. 5'-A-T-G-G-C-T-A-G-G-T-A-A-C-C-T-G-C-A-T-T-A-G-3' Table 4.5 The genetic code First Position Second Position (5' end) U C A G Third Position (3' end) Phe Ser Tyr Cys U Phe Ser Tyr Cys Leu Ser Stop Stop Leu Ser Stop Trp UCAG Leu Pro His Arg His Arg C Leu Pro Gln Arg Pro Leu Gin Arg Pro Leu Ser Asn Thr lle Ser Asn Thr lle Arg A Thr Lys UCAG UCAC G lle Arg Thr Lys Met Gly Asp Ala Val Gly Asp Ala Val Gly G Glu Ala UCAC Val Gly Glu Ala Val Note: This table identifies the amino acid encoded by each triplet. For example, the codon 5'-AUG-3' on mRNA specifies methionine, whereas CAU specifies histidine. UAA, UAG, and UGA are termination signals. AUG is part of the initiation signal, in addition to coding for internal methionine residues. Table 4.5 Biochemistry, Seventh Edition 2012 W. H. Freeman and Company B eviation: does it play abbreviation:arrow_forwardAnswer all of the questions please draw structures for major productarrow_forwardfor glycolysis and the citric acid cycle below, show where ATP, NADH and FADH are used or formed. Show on the diagram the points where at least three other metabolic pathways intersect with these two.arrow_forward
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