Principles of Biology
Principles of Biology
2nd Edition
ISBN: 9781259875120
Author: Robert Brooker, Eric P. Widmaier Dr., Linda Graham Dr. Ph.D., Peter Stiling Dr. Ph.D.
Publisher: McGraw-Hill Education
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Chapter 3, Problem 9TY
Summary Introduction

Introduction:

Proteins are the macromoleculesor large biomolecules. These are composed of one or more long chains of polypeptide chains. These are folded into simple to complex structures. These could be fibrous or round-shape. Proteins play various important roles in organisms such as providing structure to cells, DNA replication, catalyzing the metabolic reactions, transport the molecules from one place to anotherandresponse to stimuli.

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22. Which of the following mutant proteins is expected to have a dominant negative effect when over-   expressed in normal cells?   a. mutant PI3-kinase that lacks the SH2 domain but retains the kinase function   b. mutant Grb2 protein that cannot bind to RTK   c. mutant RTK that lacks the extracellular domain   d. mutant PDK that has the PH domain but lost the kinase function   e. all of the above
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Biomolecules - Protein - Amino acids; Author: Tutorials Point (India) Ltd.;https://www.youtube.com/watch?v=ySNVPDHJ0ek;License: Standard YouTube License, CC-BY