Lehninger Principles Of Biochemistry 7e & Study Guide And Solutions Manual For Lehninger Principles Of Biochemistry 7e
Lehninger Principles Of Biochemistry 7e & Study Guide And Solutions Manual For Lehninger Principles Of Biochemistry 7e
7th Edition
ISBN: 9781319125776
Author: David L. Nelson, Michael M. Cox
Publisher: W. H. Freeman
bartleby

Concept explainers

Question
Book Icon
Chapter 3, Problem 4P

(a1)

Summary Introduction

To determine: Equilibrium equations for three ionizations of histidine and assign pKa value for each ionization state.

Introduction: Amino acids are the monomer units of proteins. These are basically organic compounds consisting of a carboxylic group (-COOH) and an amino group (-NH2). Along with these functional groups, a side chain (R group) is also present in all the amino acids.

(a2)

Summary Introduction

To draw: Histidine structure in each ionization state.

Introduction: Histidine is a basic amino acid with lysine and arginine. Histidine consists of three ionizable groups. These are α-amino group, α-carboxylic acid group, and side chain amino group.

(a3)

Summary Introduction

To determine: The net charge on histidine molecule in each ionization state.

Introduction:

Histidine is a basic amino acid along with lysine and arginine. Histidine consists of three ionizable groups. These are α-amino group, α-carboxylic acid group, and side chain amino group.

(b)

Summary Introduction

To draw: The structures of histidine at pH 1, 4, 8, and 12.

Introduction:

pH is defined as the negative of base 10 logarithm of hydrogen ion concentration. It is a scale to determine the nature of an aqueous solution; acidic or alkaline.

(c1)

Summary Introduction

To determine: The net charge of histidine at pH 1, 4, 8, and 12.

Introduction:

pH is defined as the negative of base 10 logarithm of hydrogen ion concentration. It is a scale to determine the nature of an aqueous solution; acidic or alkaline.

(c2)

Summary Introduction

To determine: Whether histidine would migrate towards anode or cathode in an electric field for each pH.

Introduction:

pH is defined as the negative of base 10 logarithm of hydrogen ion concentration. It is a scale to determine the nature of an aqueous solution; acidic or alkaline.

Blurred answer
Students have asked these similar questions
Biochemistry What is the process of "transamination" in either the muscles or the liver, that involves keto acid or glutamic acid? Please explain how the steps work. Thank you!
Biochemistry Please help. Thank you What is the importance of glutamic acid in the metabolism of nitrogen from amino acids? (we know therole; it’s used to remove the nitrogen from amino acids so that the remaining carbon skeleton can bebroken down by the “usual” pathways, but what is the important, unique role that only glutamicacid/glutamate can do?)
Biochemistry Please help. Thank you When carbamyl phosphate is joined to L-ornathine, where does the energy for the reaction come from?
Knowledge Booster
Background pattern image
Biochemistry
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
Text book image
Biochemistry
Biochemistry
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:W. H. Freeman
Text book image
Lehninger Principles of Biochemistry
Biochemistry
ISBN:9781464126116
Author:David L. Nelson, Michael M. Cox
Publisher:W. H. Freeman
Text book image
Fundamentals of Biochemistry: Life at the Molecul...
Biochemistry
ISBN:9781118918401
Author:Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:WILEY
Text book image
Biochemistry
Biochemistry
ISBN:9781305961135
Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:Cengage Learning
Text book image
Biochemistry
Biochemistry
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Cengage Learning
Text book image
Fundamentals of General, Organic, and Biological ...
Biochemistry
ISBN:9780134015187
Author:John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:PEARSON