Chapter 3, Problem 3DID

Summary Introduction

To explain: The place where the CFTR protein is held up in the cells of CF-affected patient.

Introduction: Cystic fibrosis transmembrane conductance regulator (CFTR) is a plasma membrane transport protein encoded by the gene CFTR. CFTR protein is present in a few copies in the people affected by cystic fibrosis (CF). Thus, the amount of chloride ions and water that leave the cell become very less. This results in thick, dry mucus and the airways to the lungs get clogged. Chronic lung infections and difficulty in breathing are some of the symptoms associated with CF.