Chapter 3, Problem 2P

Summary Introduction

To examine:  Whether the statement “Intrinsically disordered regions of proteins can be identified using bioinformatics methods to search genes for encoded amino acid sequences that possess high hydrophobicity and low net charge” is true or false.

Introduction:

Protein are the important constituents of diet. It consists of a chain of amino acids called polypeptide. There are 20 different amino acids in proteins which are coded by organisms’ DNA. Protein forms primary, secondary, tertiary structure, and quaternary structures.  Intrinsically the disordered protein are abundant in nature. They have important functions in the interior of cells. The proteins have loop of polypeptide chains that protrude from the core region of the protein domain. These loops remain unstructured until they bind to the other molecule.