A.
To determine: The significance of pain in relation to inflammatory response.
Introduction: The anti-inflammatory drugs are the ones that reduce the inflammation or enlargement of tissues or cells caused due to several reasons like infection, release of inflammatory molecules, hypersensitivity, and so on.
A.
Explanation of Solution
The inflammatory response is accompanied by five cardinal signs of inflammation that include rubor (redness), tumor (swelling), dolor (pain), calor (increased temperature or heat) and functio laesa (loss of function). Redness and increased heat is due to increase in blood circulation in the site of inflammation. Pain is major sign of inflammation that occurs due chemicals that stimulate nerve endings especially the pain receptors. Pain occurs only when the appropriate sensory nerve endings in the inflamed site and because of the release of pain inducing chemicals like bradykinins and histamine.
B.
To determine: The cause of fever and elevated white blood cell count.
Introduction: The symptoms of local inflammation include rubor (redness), heat (calor), swelling (tumour) due to the increased flow of blood and also increased vascular permeability that is accompanied by pain (dolor) that is due to the chemical mediators acting on the pain receptors
B.
Explanation of Solution
The inflammation is caused from infection or from cell and tissue injury. The injured or infected tissue triggers the immune system of the body that recruits the defense mechanism of the body by sending white blood cells to the affected site. The macrophages constitute the largest portion of the white blood cells that reach the site of infection followed by basophils that release histamines and other inflammatory agents.
Thus, the white blood count id elevated during infection or tissue injury. Fever during inflammatory is caused by the released of substance called pyrogens that increase the blood circulation at the affected site to allow flow of inflammatory agents, macrophages, complement proteins and so on. The increase in the rate of blood circulation raises the body temperature and causes fever. Pyrogens released include interleukins, tumor necrosis factor during sever infections and stimulate the brain capillaries to produce PGE2 (prostagolandin 2) that causes inflammation.
C.
To determine: The preferred treatment for abdominal pain, fever and elevated blood count.
Introduction: The disease can be of several types and are differentiated on the basis of various parameters. Depending upon the onset of the disease symptoms and the time period of infection the diseases are divided into acute infections and chronic infections.
C.
Explanation of Solution
The abdominal pain, elevated white blood cell count (mainly neutrophils) along with fever is some common symptoms associated with many diseases like bacterial infection. Food or water borne disease or even appendicitis. Appendicitis is the inflammation of appendix from bacterial infection. The course of treatment for appendicitis include surgery in severe cases to remove appendix, antibiotics to treat bacterial infection and to prevent the possibility of post surgery sepsis, pain relievers, intravenous fluids and liquid diet.
Want to see more full solutions like this?
Chapter 3 Solutions
EBK ESSENTIALS OF PATHOPHYSIOLOGY
- If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake? Options: A. Dose; Increase dose B. Dose; Decrease dose C. Dose; Do not change dose D. Interval; Increase the interval between doses (give the drug less frequently) E. Interval; Decrease the interval between doses (give the drug more frequently) F. Interval; Do not change the intervalarrow_forwardWhat percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the matharrow_forwardBriefly explain the 6 domain of interprofessional collaboration: Role clarification, Team functioning, Interprofessional communication, Patient/client/family/community-centered care, Interprofessional conflict resolution, Collaborative leadership. Provide a specific negative events that nursing student would observe in a clinical setting for each domain.arrow_forward
- what is an intermittent water course and what kind of fish habitat it would providearrow_forwardwhy are native freshwater mussels are an important part of great lakes ecosystemarrow_forwardwhat morphological features differentiate the lamprey species and other species in the great lakesarrow_forward
- There are a wide range of therapeutic applications available as options for patients. Medical professionals should be aware of these applications so they can make informed recommendations to patients. To gain a better understanding of some therapeutic applications and how they are related to RNA and mRNA, research long non-coding RNA. Respond to the following in a minimum of 175 words: What is lncRNA and what does it do? How does IncRNA differ from mRNA? What are some therapeutic applications associated with lncRNA? Think about possible future uses of this application. What are the advantages and disadvantages of this application and its continued use?arrow_forwardfour fish or mussel species that are native to the great lakesarrow_forwardThere are a wide range of therapeutic applications available as options for patients. Medical professionals should be aware of these applications so they can make informed recommendations to patients. To gain a better understanding of some therapeutic applications and how they are related to RNA and mRNA, research long non-coding RNA. Respond to the following in a minimum of 175 words: What is lncRNA and what does it do? How does IncRNA differ from mRNA? What are some therapeutic applications associated with lncRNA? Think about possible future uses of this application. What are the advantages and disadvantages of this application and its continued use?arrow_forward
- four physial characteristics of a fish or a mussel that would help you identify it to a speciesarrow_forwarddescribe what you would do in this situation, you are working ona. river and it will take 20 minutes by boat to get back to the field truck, you are 1 hour from finishing the field work on the last day of field trip. you hear thunder int he dsitnace, what did you do?arrow_forwardunu grow because auxin is still produced in the tip to Another of Boysen and Jensen's experiments included the use of mica, explain why one of the shoots was able to show phototropism and the other was not. Mica Wafer Ligh c. They then t but this time permeable n shoot. Why phototropis Light Mica Wafer Coleoptile tips Tips removed: agar Explain why the shoo direction after the ag the cut shoot, even tarrow_forward
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education