Microbiology with Diseases by Body System (4th Edition)
4th Edition
ISBN: 9780321918550
Author: Robert W. Bauman Ph.D.
Publisher: PEARSON
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Textbook Question
Chapter 3, Problem 11TMW
Many antimicrobial drugs target bacterial cell walls. Why aren't there many drugs that act against bacterial cytoplasmic membranes?
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Which of the following types of antimicrobial drugs make microbes more susceptible
to osmotic pressure?
1) drugs that inhibit nucleic acid synthesis
O 2) drugs that inhibit metabolic pathways
3) drugs that inhibit cell wall synthesis
4) drugs that block a pathogen's recognition of its host
5) drugs that inhibit protein synthesis
Broad-spectrum drugs target a wide variety of bacterial pathogens. Even when the broad-spectrum drug is capable of killing a target pathogen, it may not be the best treatment.
Which statement best explains why a broad spectrum drug might be an undesirable treatment choice?
Broad-spectrum antimicrobials are usually toxic to the host cells.
Broad-spectrum antimicrobials only work if they are used shortly after the infection begins.
Broad-spectrum antimicrobials may kill much of the normal microbiota.
Broad-spectrum antimicrobials are not able to kill bacteria that are in their log phase of growth.
Broad-spectrum antimicrobials may stimulate excess growth of the normal microbiota.
List all the antibiotics in the above table that work through destroying the bacterial cell wall. (if there
are none listed please state that)
Chapter 3 Solutions
Microbiology with Diseases by Body System (4th Edition)
Ch. 3 - Prob. 1TMWCh. 3 - In 1985, an Israeli scientist discovered the...Ch. 3 - Why is a pilus a type of fimbria, but a flagellum...Ch. 3 - Why is the microbe illustrated in Figure 3.2 more...Ch. 3 - When the bacterium Escherichia coli is grown in a...Ch. 3 - Prob. 6TMWCh. 3 - Why do scientists consider bacterial and archaeal...Ch. 3 - Why did scientists in the 19th and early 20th...Ch. 3 - Why do some scientists consider archaea, which are...Ch. 3 - Why are eukaryotic glycocalyces covalently bound...
Ch. 3 - Many antimicrobial drugs target bacterial cell...Ch. 3 - Colchicine is a drug that inhibits microtubule...Ch. 3 - A cell may allow a large or charged chemical to...Ch. 3 - Which of the following statements concerning...Ch. 3 - A 9 + 2 arrangement of microtubules is seen in...Ch. 3 - Which of the following is most associated with...Ch. 3 - Which of the following is not associated with...Ch. 3 - Which of the following is true of Svedbergs? a....Ch. 3 - Which of the following statements is true? a. The...Ch. 3 - Prob. 8MCCh. 3 - Bacterial flagella are ______________. a. anchored...Ch. 3 - Prob. 10MCCh. 3 - A Gram-negative cell is moving uric acid across...Ch. 3 - Gram-positive bacteria _______________. a. have a...Ch. 3 - Endospores ________________. a. are reproductive...Ch. 3 - Prob. 14MCCh. 3 - Dipicolinic acid is an important component of...Ch. 3 - Match the structures on the left with the...Ch. 3 - Match the term on the left with its description on...Ch. 3 - Label the structures of the following prokaryotic...Ch. 3 - Label each type of flagellar arrangement.Ch. 3 - A scientist who is studying passive movement of...Ch. 3 - Describe (or draw) an example of diffusion down a...Ch. 3 - Sketch, name, and describe three flagellar...Ch. 3 - Prob. 3SACh. 3 - The term fluid mosaic has been used in describing...Ch. 3 - A local newspaper writer has contacted you, an...Ch. 3 - Prob. 6SACh. 3 - Compare bacterial cells and algal cells, giving at...Ch. 3 - Contrast a cell of Streptococcus pyogenes (a...Ch. 3 - Differentiate among pili, fimbriae, and cilia,...Ch. 3 - Prob. 10SACh. 3 - Prob. 11SACh. 3 - Prob. 12SACh. 3 - What is the function of glycocalyces and fimbriae...Ch. 3 - Prob. 14SACh. 3 - Compare and contrast three types of passive...Ch. 3 - Prob. 16SACh. 3 - Prob. 17SACh. 3 - Prob. 18SACh. 3 - Prob. 1CTCh. 3 - Methylene blue binds to DNA. What structures in a...Ch. 3 - Prob. 3CTCh. 3 - Prob. 4CTCh. 3 - A researcher carefully inserts an electrode into...Ch. 3 - Prob. 6CTCh. 3 - An electron micrograph of a newly discovered cell...Ch. 3 - An entry in a recent scientific journal reports...Ch. 3 - Prob. 9CTCh. 3 - Prob. 10CTCh. 3 - Prob. 11CTCh. 3 - Prob. 12CTCh. 3 - Prob. 13CTCh. 3 - Prob. 14CTCh. 3 - Using the following terms, fill in the following...
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- Given that both human cells and pathogens synthesize proteins at ribosomal sites, how can antimicrobial agents that target this process be safe to use in humans?arrow_forwardMany antibiotics used in modern medicine are compounds made by fungi that inhibit bacterial protein synthesis. Describe the specific effect of the following antimicrobial drugs: (i) Tetracycline (ii) Puromycin (iii) Alpha-Amanitinarrow_forwardWhat bacterial structural target would make an antibacterial drug selective for gram-negative bacteria? Provide one example of an antimicrobial compound that targets this structure.arrow_forward
- 1) Match the antibiotics with their mechanism of action: mechnism of action: 1) nucleic acid synthesis inhibitor 2) Cell wall synthesis inhibitor 3) cell membrane disruptor 4) protein synthesis inhibitor 5) folic acid synthesis inhibitorarrow_forwardCould an organism that is susceptible to an antimicrobial agent in laboratory testing fail to respond to it when that drug is used to treat the patient? Explain.arrow_forwardMost medically useful antibiotics interfere with either peptidoglycan synthesis or ribosome function. Why would the cell membrane be a poor target for antimicrobial medication?arrow_forward
- Some antibiotics fail to kill/inhibit a pathogen simply because the microbe is naturally (intrinsically) resistant to it. True or False ?arrow_forwardMany antibiotics used in modern medicine are compounds made by fungi that inhibit bacterial protein synthesis. Describe the specific effect of the following antimicrobial drugs: (i) Chloramphenicol (ii) Rifamycinarrow_forwardWhy do most antibacterial drugs not destroy human cells?arrow_forward
- Some bacteria produce the enzyme penicillinase, which breaks the beta-lactam ring in the penicillin molecule and converts it into penicilloic acid, which is harmless to bacteria. This is an example of which of the following mechanisms of antibiotic resistance? which option below is the answer? Destruction or inactivation of the antibiotic by the microbe Preventing penetration to the target site within the microbe Alteration of the drug’s target site(s) within the microbe None of the other four answers are correct Rapid ejection (pumping) of the drug out of the microbial cellarrow_forwardAnswer all of the questions 1. Which of the following antimicrobial drugs target DNA/RNA synthesis? a) Ciprofloxacin b) Sulfa drugs c) Gentamycin d) Penicilline) Polymyxin B 2. Which of the following antimicrobial drugs target protein synthesis? a) Ciprofloxacin b) Sulfa drugs c) Gentamycin d) Penicilline) Polymyxin B 3. true or false: Streptococcus is killed by growing on blood agar.arrow_forwardWhy are certain anti-bacterial agents more effective at killing bacteria?arrow_forward
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USMLE-Rx Antimicrobial Therapy; Author: USMLE-Rx;https://www.youtube.com/watch?v=Pka1Ynlrqtw;License: Standard Youtube License