Brock Biology of Microorganisms (15th Edition)
15th Edition
ISBN: 9780134261928
Author: Michael T. Madigan, Kelly S. Bender, Daniel H. Buckley, W. Matthew Sattley, David A. Stahl
Publisher: PEARSON
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Chapter 29.4, Problem 3MQ
Summary Introduction
The basic reproduction number in epidemiology is called as the basic reproductive ratio and it is denoted as R0. This metric system is beneficial because it helps to determine the status of infectious disease that can be developed in a population. Generally, the value of basic reproduction number R0 is larger to manage the epidemic.
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 29 Solutions
Brock Biology of Microorganisms (15th Edition)
Ch. 29.1 - Prob. 1MQCh. 29.1 - Prob. 2MQCh. 29.1 - Which is more severe, a disease with a high...Ch. 29.1 - Distinguish between disease incidence and disease...Ch. 29.2 - Explain coevolution of host and pathogen. Cite a...Ch. 29.2 - How does herd immunity prevent a nonimmune...Ch. 29.2 - Prob. 1CRCh. 29.3 - Prob. 1MQCh. 29.3 - Prob. 2MQCh. 29.3 - Prob. 3MQ
Ch. 29.3 - Prob. 1CRCh. 29.4 - Distinguish between direct and indirect...Ch. 29.4 - Prob. 2MQCh. 29.4 - Prob. 3MQCh. 29.4 - Prob. 1CRCh. 29.5 - Prob. 1MQCh. 29.5 - Outline the steps taken to eradicate smallpox.Ch. 29.5 - Describe some of the public health activities of...Ch. 29.5 - Prob. 1CRCh. 29.6 - Prob. 1MQCh. 29.6 - Prob. 2MQCh. 29.6 - Contrast the leading causes of death in Africa and...Ch. 29.7 - Prob. 1MQCh. 29.7 - What factors are important in the emergence or...Ch. 29.7 - Prob. 3MQCh. 29.7 - QHow can bacterial genetic exchange fuel the...Ch. 29.8 - Prob. 1MQCh. 29.8 - Prob. 2MQCh. 29.8 - What is a reassortant influenza virus and why can...Ch. 29.8 - Prob. 1CRCh. 29.9 - Prob. 1MQCh. 29.9 - Prob. 2MQCh. 29.9 - Why are smallpox and anthrax more likely to be...Ch. 29 - Prob. 1AQCh. 29 - Prob. 2AQCh. 29 - Prob. 3AQ
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