EBK PRINCIPLES OF BIOLOGY
2nd Edition
ISBN: 8220103675338
Author: BROOKER
Publisher: YUZU
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Chapter 29.2, Problem 1CC
Summary Introduction
To write:
The role of auxin carriers to allow auxin to move upward in roots.
Introduction:
Plant hormone auxin is produced in the stem, bud and root tips help to promote stem elongation, inhibits the growth of lateral buds. The chemical substance helps in regulating the action of certain cells.
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Linuron, a derivative of urea, is used as an herbicide. Linuron serum levels were measured in 4Kg
rabbits following a bolus IV injection of 10mg/kg.
Time (minutes)
Serum Linuron Levels (ug/ml)
following IV dose
10
15.48
20
8.60
30
5.90
45
3.78
60
2.42
90
1.49
120
0.93
180
0.60
240
0.41
300
0.29
360
0.22
Analyze this data and perform the necessary calculations to determine the following pharmacokinetic
parameters from the IV data: (5 points per parameter, 24 parameters/variables ■ 120 points
possible). You do NOT need to submit graphs or data tables.
Give the terminal regression line equation and R or R² value:
Give the x axis (name and units, if any) of the terminal line:
Give the y axis (name and units, if any) of the terminal line:
Give the residual regression line equation and R or R² value:
Give the x axis (name and units, if any) of the residual line:
Give the y axis (name and units, if any) of the residual line:
Chapter 29 Solutions
EBK PRINCIPLES OF BIOLOGY
Ch. 29.1 - Prob. 1BCCh. 29.1 - Prob. 1TYKCh. 29.2 - Prob. 1CCCh. 29.2 - Prob. 2CCCh. 29.2 - Prob. 1TYKCh. 29.2 - Prob. 2TYKCh. 29.3 - What kind of light does the active conformation of...Ch. 29.3 - Prob. 2CCCh. 29.3 - Imagine a garden that has been planted with...Ch. 29.3 - Prob. 3CC
Ch. 29.4 - Prob. 1CCCh. 29.4 - Prob. 1TYKCh. 29.5 - Prob. 1CCCh. 29.5 - In what way is systemic acquired resistance to...Ch. 29.5 - Prob. 1TYKCh. 29 - Prob. 1TYCh. 29 - Prob. 2TYCh. 29 - Prob. 3TYCh. 29 - Prob. 4TYCh. 29 - Prob. 5TYCh. 29 - Photoreceptor molecules allow plant cells to...Ch. 29 - Prob. 7TYCh. 29 - Prob. 8TYCh. 29 - Prob. 1CCQCh. 29 - Prob. 2CCQCh. 29 - Prob. 3CCQCh. 29 - Prob. 1CBQCh. 29 - How could you increase the resistance of a...
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