The chemical constituents of prions. Introduction: Prions refer to infectious particles composed of proteins that can undergo multiple folding patterns and are capable of causing infectious diseases. The name prion is derived from proteinaceous infectious particle. It is an agent that does not depend on genes that involve RNA or DNA for transmission. The protein that prions are made of is found throughout the body, even in healthy people and animals. However, prions isolated from diseases were found to resist action of proteases. These prions are responsible for neuro degenerative diseases such as kuru in humans and bovine spongiform encephalopathy (BSE) in cattle.

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Chapter 28.5, Problem 10A

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The chemical constituents of prions.

Introduction:

Prions refer to infectious particles composed of proteins that can undergo multiple folding patterns and are capable of causing infectious diseases. The name prion is derived from proteinaceous infectious particle. It is an agent that does not depend on genes that involve RNA or DNA for transmission. The protein that prions are made of is found throughout the body, even in healthy people and animals. However, prions isolated from diseases were found to resist action of proteases. These prions are responsible for neuro degenerative diseases such as kuru in humans and bovine spongiform encephalopathy (BSE) in cattle.

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