The reason for the results to suggest that the hypothesis is correct. Introduction: Warm-acclimated animals such as groundhogs, bears, bats, and gophers are the animals that maintain constant body temperature and do not need external factors such as shade or sunlight. Shivering is a mechanism in response to cold. If the core body temperature goes down, shivering reflex is induced in order to maintain homeostasis. During shivering, the skeletal muscles start to shake in small movements, thereby generating warmth by spending energy

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The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions. 1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction? 2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe: a) What molecule do you recommend for the trial. Why? b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for? 3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale. 4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale. Mutation 1 Mutation 2

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Chapter 28.3, Problem 2I

Summary Introduction

To explain: The reason for the results to suggest that the hypothesis is correct.

Introduction: Warm-acclimated animals such as groundhogs, bears, bats, and gophers are the animals that maintain constant body temperature and do not need external factors such as shade or sunlight. Shivering is a mechanism in response to cold. If the core body temperature goes down, shivering reflex is induced in order to maintain homeostasis. During shivering, the skeletal muscles start to shake in small movements, thereby generating warmth by spending energy

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The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions. 1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction? 2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe: a) What molecule do you recommend for the trial. Why? b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for? 3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale. 4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale. Mutation 1 Mutation 2

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