
Introduction:
Ms. Johansen, a 38-year-old lady, is 26 weeks pregnant. Three weeks ago, she was diagnosed with preeclampsia and antihypertensive drugs were administered. She complains about a constant headache and exhibits edema. Moreover, her blood pressure rises continuously and is noted as 162/109 mmHg (millimeter of mercury). Her urinalysis has been analyzed to be positive for protein. Blood tests to determine platelet levels, as well as liver function, has been ordered by the doctor. The doctor advised her to put off the delivery if possible as the premature babies are highly prone to various health problems. Nonclosure of ductus arteriosus is one such problem.

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Chapter 28 Solutions
Human Anatomy & Physiology Plus Modified Mastering A&P with Pearson eText -- Access Card Package 11th edition
- 1. Match each vocabulary term to its best descriptor A. affinity B. efficacy C. inert D. mimic E. how drugs move through body F. how drugs bind Kd Bmax Agonist Antagonist Pharmacokinetics Pharmacodynamicsarrow_forward50 mg dose of a drug is given orally to a patient. The bioavailability of the drug is 0.2. What is the volume of distribution of the drug if the plasma concentration is 1 mg/L? Be sure to provide units.arrow_forwardDetermine Kd and Bmax from the following Scatchard plot. Make sure to include units.arrow_forward
- Choose a catecholamine neurotransmitter and describe/draw the components of the synapse important for its signaling including synthesis, packaging into vesicles, receptors, transporters/degradative enzymes. Describe 2 drugs that can act on this system.arrow_forwardThe following figure is from Caterina et al. The capsaicin receptor: a heat activated ion channel in the pain pathway. Nature, 1997. Black boxes indicate capsaicin, white circles indicate resinferatoxin. a) Which has a higher potency? b) Which is has a higher efficacy? c) What is the approximate Kd of capsaicin in uM? (you can round to the nearest power of 10)arrow_forwardWhat is the rate-limiting-step for serotonin synthesis?arrow_forward
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