Biochemistry
Biochemistry
8th Edition
ISBN: 9781464126109
Author: Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr., Lubert Stryer
Publisher: W. H. Freeman
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Chapter 28, Problem 17P
Interpretation Introduction

Interpretation:

The reason for the oxidation of guanine bases resulting in the expansion of the triplet repeat needs to be explained.

Concept introduction:

Out of all the 4 DNA bases only guanine has the lowest reduction potential. Therefore, it is easily oxidized. Guanine oxidation products results in G: C − T: A transversion through means of DNA replications.

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