Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Chapter 28, Problem 14P
Interpretation Introduction
Interpretation:
To determine the given KI and I50 values. Whether the compound A is effective in preventing HIV replication when taken orally or not should be determined.
Concept introduction:
The IC50, half maximal inhibitory concentration, is the capacity of a substance to inhibit biological molecules and biochemical reactions. IC50 is the quantitative measurement of the inhibitor, which indicates the amount of inhibitor required to inhibit the biological substance.
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