Brock Biology of Microorganisms (14th Edition)
Brock Biology of Microorganisms (14th Edition)
14th Edition
ISBN: 9780321897398
Author: Michael T. Madigan, John M. Martinko, Kelly S. Bender, Daniel H. Buckley, David A. Stahl, Thomas Brock
Publisher: PEARSON
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Chapter 26.9, Problem 2MQ
Summary Introduction

B and T cells need extra molecular signals for activation in addition to the interaction of antigens through T cell receptors (TCRs) or immunoglobulins (Igs). In case, these signals are absent this may result in unresponsive B and T cells, even if exposed to self-antigens. This mechanism plays an important role in preventing autoimmunity.

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