EBK HUMAN PHYSIOLOGY
EBK HUMAN PHYSIOLOGY
7th Edition
ISBN: 9780133983401
Author: Silverthorn
Publisher: YUZU
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Chapter 26, Problem 21RQ

The following graph shows the results of an experiment in which normal men were given testosterone over a period of months (indicated by the bar from A to E). Control values of hormones were measured prior to the start of the experiment. From time B to time C, the men were also given FSH. From time D to time E, they were also given LH. Based on the information given, answer the following questions.

Chapter 26, Problem 21RQ, The following graph shows the results of an experiment in which normal men were given testosterone

  1. (a) Why did testosterone level increase beginning at point A?
  2. (b) Why did LH and FSH levels decrease beginning at point A?
  3. (c) Predict what happened to the men’s sperm production in the A–B interval, the B–C interval, and the D–E interval.
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Students have asked these similar questions
a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.  b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake? Options: A. Dose; Increase dose     B. Dose; Decrease dose     C. Dose; Do not change dose     D. Interval; Increase the interval between doses (give the drug less frequently)    E. Interval; Decrease the interval between doses (give the drug more frequently)     F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math

Chapter 26 Solutions

EBK HUMAN PHYSIOLOGY

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