The opinion for the given statement “Cholesterol plays an essential role in the body, making cells, hormones and tissues” should be determined. Concept introduction: When the levels of cholesterol rise abruptly then it is a condition known as hypercholesterolemia. When this disease is genetic then it is known as familial hypercholesterolemia. In this disease, the concentration of cholesterol is very high even in young children. Causes of familial hypercholesterolemia are a mutation that results in this disease. Also, the malfunctioning of the Low-Density Lipoprotein (LDL) receptor results in this disease.

Question

The preferred substrate is T because the enzyme half-saturates at 7.00 mM for T, but requires 28.0 mM for U, and 112 mM for S. b Question Content Area The rate constant k 2 with substrate S is 9.60×107 sec-1, with substrate T, k 2 = 6.00×104 sec-1, and with substrate U, k 2 = 2.40×106 sec-1. Calculate the catalytic efficiency with S, T, and U. Catalytic efficiency with S = Catalytic efficiency with T = Catalytic efficiency with U = Does enzyme A use substrate S, substrate T, or substrate U with greater catalytic efficiency?

Answer 1

Question

Chapter 26, Problem 21P

Interpretation Introduction

Interpretation:

The opinion for the given statement “Cholesterol plays an essential role in the body, making cells, hormones and tissues” should be determined.

Concept introduction:

When the levels of cholesterol rise abruptly then it is a condition known as hypercholesterolemia. When this disease is genetic then it is known as familial hypercholesterolemia. In this disease, the concentration of cholesterol is very high even in young children. Causes of familial hypercholesterolemia are a mutation that results in this disease. Also, the malfunctioning of the Low-Density Lipoprotein (LDL) receptor results in this disease.

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