Biology: Concepts and Investigations
Biology: Concepts and Investigations
3rd Edition
ISBN: 9780073525549
Author: Mariëlle Hoefnagels Dr.
Publisher: McGraw-Hill Education
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Chapter 25.4, Problem 3MC
Summary Introduction

To determine:

The difference between positive and negative feedback.

Concept introduction:

Homeostasis is a condition when there is balance maintained between the external environments to the internal environment. It is a state of stabilized internal environment. To maintain homeostasis, internal mechanisms use positive and negative feedback.

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You aim to test the hypothesis that the Tbx4 and Tbx5 genes inhibit each other's expression during limb development. With access to chicken embryos and viruses capable of overexpressing Tbx4 and Tbx5, describe an experiment to investigate whether these genes suppress each other's expression in the limb buds. What results would you expect if they do repress each other? What results would you expect if they do not repress each other?
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