CUSTOMIZED LAB MANUAL FOR BIOLOGY 1406
CUSTOMIZED LAB MANUAL FOR BIOLOGY 1406
14th Edition
ISBN: 9781307716474
Author: Mader
Publisher: MCG
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Chapter 25.4, Problem 2LO
Summary Introduction

To compare:

The gene regulation in prokaryotes with the gene regulation in eukaryotes.

Given:

Regulation of gene expression includes a wide range of mechanisms that are used by cells to increase or decrease the production of specific gene products (protein or RNA).

Introduction:

Gene expression can be characterized as the procedure by which the information encoded in a gene is utilized to coordinate the assembly of protein molecule. Gene expression is explored via a study of the protein function and structure, translation and transcription, stem cells and differentiated cells.

These products are often proteins, but in non-protein coding genes such as ribosomal RNA (rRNA), transfer RNA (tRNA) or small nuclear RNA (snRNA) genes, the product is a functional RNA. The process of gene expression is used by all known life - eukaryotes (including multicellular organisms), prokaryotes (bacteria and archaea).

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Imagine that you are a clinical geneticist. Your colleague is an oncologist who wants your help explaining the basics of genetics to their patient, who will be undergoing genetic testing in the coming weeks for possible acute myeloid leukemia (AML) induced by the radiation she had several years ago for breast cancer. Write a 1,050- to 1,225-word memo to your colleague. Include the following in your memo: An explanation of the molecular structure of DNA and RNA, highlighting both similarities and differences  A description of the processes of transcription and translation An explanation of the differences between leading and lagging strands and how the DNA is replicated in each strand Reponses to the following common questions patients might ask about this type of genetic testing and genetic disorder: Does AML run in families? What genes are tested for?
Respond to the following in a minimum of 175 words: What are some potential consequences that could result if the processes of replication, transcription, and translation don’t function correctly? Provide an example of how you might explain these consequences in terms that patients might understand.
answer questions 1-10

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CUSTOMIZED LAB MANUAL FOR BIOLOGY 1406

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