Analysis of sclerotia and conidia formation in the filamentous ascomycete Aspergillus flavus suggests that formation of these structures is cell density dependent. Specifically, high cell density cultures yield conidia, whereas low cell density triggers sclerotia formation. Review the structure and function of conidia and sclerotia, and formulate a hypothesis to explain why their development would be regulated in a density-dependent manner. List several specific testable predictions based on your hypothesis.
Read the original paper: Horowitz-Brown, S., et al. 2008. Morphological transitions governed by density dependence and lipooxygenase activity in Aspergillus flavus. Appl. Environ. Microbiol. 74:5674.

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