Laboratory Experiments in Microbiology (11th Edition)
11th Edition
ISBN: 9780321994936
Author: Ted R. Johnson, Christine L. Case
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Videos
Textbook Question
Chapter 25, Problem 3Q
Why is the disk-diffusion technique not a perfect indication of how the drug will perform in vivo? What other factors are considered before using the antimicrobial agent in vivo?
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
How are dilution susceptibility tests and disc diffusion tests usedto determine microbial drug sensitivity?
What are the tests to determine the level of antimicrobial activity of a antimicrobial agent? How dilution susceptibility and disk diffusion test can be used to determine the effectiveness of a drug?
Why is the effectiveness of an antimicrobial agent determined using an exponentially growing bacterial culture? Please explain.
Chapter 25 Solutions
Laboratory Experiments in Microbiology (11th Edition)
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- What is the main group of microorganisms producing the most antibiotics? Describe the biochemical characteristics of this microorganism and provide TWO (2) examples of antibiotics produced by these microbes.arrow_forwardWhat bacterial structural target would make an antibacterial drug selective for gram-negative bacteria? Provide one example of an antimicrobial compound that targets this structure.arrow_forwardPolymer nanoparticles, Microparticles and hydrogels have been developed for slow and sustained drug release for slow and sustained drug release application; mark all that apply below: 1)Drug release from hydrogels can be via (a) drug diffusion, (b) degradation of the polymeric matrix and (c) swelling 2) PLGA degrades to lactic acid and glycolic acid, which are not biocompatible 3) Drug release can be triggered through internal and external stimuli - I.e. by use of pH labile chemistries or external triggers 4) Burst release describes the initial faster release rates often observed in drug delivery system, which is then followed by sustained release 5) while burst release is observed with polymer nanoparticles, it is not observed from hydrogelsarrow_forward
- Discuss the procedure and application for the agar well diffusion method of evaluating antimicrobial activity.arrow_forwardWhat are the two most Resistant, and the two most Sensitive microbial structures to antiseptic treatments? Why are these so?arrow_forwardWhy is it better for a drug to be microbicidal than microbistatic?arrow_forward
- The reason why most antibiotics as oral suspension dosage forms are commercially available as dry powders, to be reconstituted with water just prior to dispensing, is:arrow_forwardWhy are antimicrobials only directly effective against bacteria and what is the control on the antimicrobial plate?arrow_forwardPatch clamp What is patch clamp technique? Identify two features of the patch clamp technique that make it a useful tool in studying cellular electrophysiology. Explain each thoroughly. What is the role of the reference electrode in the patch clamp technique? Discuss how it works.arrow_forward
- Could an organism that is susceptible to an antimicrobial agent in laboratory testing fail to respond to it when that drug is used to treat the patient? Explain.arrow_forwardWhat is the purpose of the negative and positive control in the Disc diffusion assay? Why is it important to use positive and negative controls in microbial experimentation? What does it tell us if the positive control leaves a zone of inhibition but the experimental treatment (penicillin disc) does not?arrow_forwardhow is the 0.5 McFarland standard prepared? What is the role of this standard in performing antimicrobial susceptibility test?arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Principles Of Radiographic Imaging: An Art And A ...Health & NutritionISBN:9781337711067Author:Richard R. Carlton, Arlene M. Adler, Vesna BalacPublisher:Cengage Learning
Principles Of Radiographic Imaging: An Art And A ...
Health & Nutrition
ISBN:9781337711067
Author:Richard R. Carlton, Arlene M. Adler, Vesna Balac
Publisher:Cengage Learning
Infection Prevention and Control; Author: thecityoftoronto;https://www.youtube.com/watch?v=jx9sRYmBW3Q;License: Standard Youtube License