The reason behind the compounds that inhibits the activity of DNA polymerases enzyme would be an effective anticancerous agent. Introduction: DNA polymerase is an important enzyme that plays an essential role in the polymerization of nucleotides to form DNA double helical structure. It adds deoxyribonucleotide triphosphates (dNTPs act as a substrate for DNA pol) to the structure. However, the oxidized form of dNTP inhibits this enzyme. Therefore, oxidized dNTPs can act as an anti-cancerous agent in the cell.

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Definition Definition Chemical process in which one or more monomers combine to produce a very large chain-like molecule called a polymer. The functional groups present on the monomers and their steric effects are responsible for polymerization through a sequence of reactions that vary in complexity. There exists a stable covalent chemical bond between monomers that sets apart polymerization from other processes.

Chapter 25, Problem 20E

Summary Introduction

To explain: The reason behind the compounds that inhibits the activity of DNA polymerases enzyme would be an effective anticancerous agent.

Introduction: DNA polymerase is an important enzyme that plays an essential role in the polymerization of nucleotides to form DNA double helical structure. It adds deoxyribonucleotide triphosphates (dNTPs act as a substrate for DNA pol) to the structure. However, the oxidized form of dNTP inhibits this enzyme. Therefore, oxidized dNTPs can act as an anti-cancerous agent in the cell.

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The preferred substrate is T because the enzyme half-saturates at 7.00 mM for T, but requires 28.0 mM for U, and 112 mM for S. b Question Content Area The rate constant k 2 with substrate S is 9.60×107 sec-1, with substrate T, k 2 = 6.00×104 sec-1, and with substrate U, k 2 = 2.40×106 sec-1. Calculate the catalytic efficiency with S, T, and U. Catalytic efficiency with S = Catalytic efficiency with T = Catalytic efficiency with U = Does enzyme A use substrate S, substrate T, or substrate U with greater catalytic efficiency?

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Definition Definition Chemical process in which one or more monomers combine to produce a very large chain-like molecule called a polymer. The functional groups present on the monomers and their steric effects are responsible for polymerization through a sequence of reactions that vary in complexity. There exists a stable covalent chemical bond between monomers that sets apart polymerization from other processes.

Chapter 25, Problem 20E

Summary Introduction

To explain: The reason behind the compounds that inhibits the activity of DNA polymerases enzyme would be an effective anticancerous agent.

Introduction: DNA polymerase is an important enzyme that plays an essential role in the polymerization of nucleotides to form DNA double helical structure. It adds deoxyribonucleotide triphosphates (dNTPs act as a substrate for DNA pol) to the structure. However, the oxidized form of dNTP inhibits this enzyme. Therefore, oxidized dNTPs can act as an anti-cancerous agent in the cell.

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Answer 3

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Definition Definition Chemical process in which one or more monomers combine to produce a very large chain-like molecule called a polymer. The functional groups present on the monomers and their steric effects are responsible for polymerization through a sequence of reactions that vary in complexity. There exists a stable covalent chemical bond between monomers that sets apart polymerization from other processes.

Chapter 25, Problem 20E

Summary Introduction

To explain: The reason behind the compounds that inhibits the activity of DNA polymerases enzyme would be an effective anticancerous agent.

Introduction: DNA polymerase is an important enzyme that plays an essential role in the polymerization of nucleotides to form DNA double helical structure. It adds deoxyribonucleotide triphosphates (dNTPs act as a substrate for DNA pol) to the structure. However, the oxidized form of dNTP inhibits this enzyme. Therefore, oxidized dNTPs can act as an anti-cancerous agent in the cell.

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Check out a sample textbook solution

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Answer 4

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Definition Definition Chemical process in which one or more monomers combine to produce a very large chain-like molecule called a polymer. The functional groups present on the monomers and their steric effects are responsible for polymerization through a sequence of reactions that vary in complexity. There exists a stable covalent chemical bond between monomers that sets apart polymerization from other processes.

Chapter 25, Problem 20E

Summary Introduction