FUNDAMENTALS OF BIOCHEM.-NEXTGEN ACCESS
FUNDAMENTALS OF BIOCHEM.-NEXTGEN ACCESS
5th Edition
ISBN: 9781119661450
Author: Voet
Publisher: WILEY
bartleby

Concept explainers

bartleby

Videos

Question
Book Icon
Chapter 25, Problem 15E
Summary Introduction

To draw: The 5BU-G base pair.

Concept introduction: A base analogue is a chemical which that has a similar structure of either a purine or a pyrimidine is called a base analogue. 5-Bromouracil (5BU) is the base analogue that has a similar structure to that of the pyrimidine thymine. Therefore, this structure replaces or substitutes thymine present in a DNA structure and pairs it with adenine. The enol form of 5-Bromouracil causes the tautomeric shift of 5-Bromouracil. This enol form pairs with the guanine base, rather than binding to the adenine.

Summary Introduction

To explain: The type of mutation that results in the 5BU-G base pair.

Concept introduction: A base analogue is a chemical that has a similar structure of either a purine or a pyrimidine. 5-Bromouracil (5BU) is the base analogue that has a similar structure to that of the pyrimidine thymine. Therefore, this structure replaces or substitutes thymine present in a DNA structure and pairs with adenine. The enol form of 5-Bromouracil causes the tautomeric shift in 5-Bromouracil. This enol form pairs with the guanine base, rather than binding to the adenine.

Blurred answer
Students have asked these similar questions
Biochemistry Question. Please help solve. Thank you! Based upon knowledge of oxidation of bioorganic compounds and howmuch energy is released during their oxidation, rank the following, from most to least, with respect to how much energy would be produced from each during their oxidation. Explain your placement for each one.
Biochemistry Question.For the metabolism of amino acids what is the first step for theirbreakdown? Why is it necessary for this breakdown product to be transported to the liver? For the catabolism of the carbon backbone of these amino acids, there are 7 entry points into the “standard” metabolic pathways. List these 7 entry points and which amino acids are metabolized to these entry points. Please help. Thank you!
Biochemistry Question. Please help. Thank you.   You are studying pyruvate utilization in mammals for ATP production under aerobic conditions and have synthesized pyruvate with Carbon #1 labelled with radioactive C14.   After only one complete cycle of the TCA cycle, which of the TCA cycle intermediates would be labeled with C14? Explain your answer.   Interestingly, you find C14 being excreted in the urine. How does it get there?
Knowledge Booster
Background pattern image
Biochemistry
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
Text book image
Biochemistry
Biochemistry
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:W. H. Freeman
Text book image
Lehninger Principles of Biochemistry
Biochemistry
ISBN:9781464126116
Author:David L. Nelson, Michael M. Cox
Publisher:W. H. Freeman
Text book image
Fundamentals of Biochemistry: Life at the Molecul...
Biochemistry
ISBN:9781118918401
Author:Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:WILEY
Text book image
Biochemistry
Biochemistry
ISBN:9781305961135
Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:Cengage Learning
Text book image
Biochemistry
Biochemistry
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Cengage Learning
Text book image
Fundamentals of General, Organic, and Biological ...
Biochemistry
ISBN:9780134015187
Author:John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:PEARSON
Genome Annotation, Sequence Conventions and Reading Frames; Author: Loren Launen;https://www.youtube.com/watch?v=MWvYgGyqVys;License: Standard Youtube License