To propose a mechanism for the following reaction, which occurs by an initial conjugate addition followed by internal amide formation.

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Chapter 24.SE, Problem 42MP

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To propose a mechanism for the following reaction, which occurs by an initial conjugate addition followed by internal amide formation.

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The SN 1 mechanism starts with the rate-determining step which is the dissociation of the alkyl halide into a carbocation and a halide ion. The next step is the rapid reaction of the carbocation intermediate with the nucleophile; this step completes the nucleophilic substitution stage. The step that follows the nucleophilic substitution is a fast acid-base reaction. The nucleophile now acts as a base to remove the proton from the oxonium ion from the previous step, to give the observed product. Draw a curved arrow mechanism for the reaction, adding steps as necessary. Be sure to include all nonzero formal charges. Cl: Add/Remove step G Click and drag to start drawing a structure.

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Answer 2

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Chapter 24.SE, Problem 42MP

Interpretation Introduction

Interpretation:

To propose a mechanism for the following reaction, which occurs by an initial conjugate addition followed by internal amide formation.

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Answer 3

Question

Chapter 24.SE, Problem 42MP

Interpretation Introduction

Interpretation:

To propose a mechanism for the following reaction, which occurs by an initial conjugate addition followed by internal amide formation.

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Answer 4

Question

Chapter 24.SE, Problem 42MP

Interpretation Introduction

Interpretation:

To propose a mechanism for the following reaction, which occurs by an initial conjugate addition followed by internal amide formation.

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Answer 5

Chapter 24.SE, Problem 42MP

Interpretation Introduction

Interpretation:

To propose a mechanism for the following reaction, which occurs by an initial conjugate addition followed by internal amide formation.

Answer 6

Chapter 24.SE, Problem 42MP

Interpretation Introduction

Interpretation:

To propose a mechanism for the following reaction, which occurs by an initial conjugate addition followed by internal amide formation.

Answer 7

Chapter 24.SE, Problem 42MP

Interpretation Introduction

Interpretation:

To propose a mechanism for the following reaction, which occurs by an initial conjugate addition followed by internal amide formation.

Answer 8

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Ch. 24.1 - Name the following compounds:Ch. 24.1 - Prob. 2P Ch. 24.1 - Prob. 3P Ch. 24.3 - Prob. 4P Ch. 24.3 - The benzylammonium ion (C6H5CH2NH3+) has pKa =...Ch. 24.4 - Prob. 6P Ch. 24.5 - Prob. 7P Ch. 24.6 - Prob. 8P Ch. 24.6 - Prob. 9P Ch. 24.6 - Show two methods for the synthesis of dopamine, a...

To propose a mechanism for the following reaction, which occurs by an initial conjugate addition followed by internal amide formation.

Solution Summary: The author proposes a mechanism for the reaction, which occurs by an initial conjugate addition followed by internal amide formation.

Interpretation:

To propose a mechanism for the following reaction, which occurs by an initial conjugate addition followed by internal amide formation.

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Chapter 24 Solutions

To propose a mechanism for the following reaction, which occurs by an initial conjugate addition followed by internal amide formation.

Solution Summary: The author proposes a mechanism for the reaction, which occurs by an initial conjugate addition followed by internal amide formation.

Interpretation: To propose a mechanism for the following reaction, which occurs by an initial conjugate addition followed by internal amide formation.

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Chapter 24 Solutions

Interpretation:

To propose a mechanism for the following reaction, which occurs by an initial conjugate addition followed by internal amide formation.