ORGANIC CHEMISTRY
ORGANIC CHEMISTRY
9th Edition
ISBN: 9780134645704
Author: WADE AND SIMEK
Publisher: PEARSON
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Chapter 24.9C, Problem 24.21P

(a)

Interpretation Introduction

To determine: The mechanism for the reaction of the N terminus of the peptide with 2,4-dinitrofluorobenzene.

Interpretation: The mechanism for the reaction of the N terminus of the peptide with 2,4-dinitrofluorobenzene is to be determined.

Concept introduction: The process in which a proper series of amino acids is maintained in the  peptide chain is known as edmann degradation. this process includes the labelling of terminal amino residue  followed by the cleavage of this terminal amino residue from the peptide chain. the peptide bonds between other amino acids do not get disturb during this process.

(b)

Interpretation Introduction

To determine: The reason that the Edman degradation is usually preferred over the Sanger method.

Interpretation: The reason that the Edman degradation is usually preferred over the Sanger method is to be determined.

Concept introduction: The process in which a proper series of amino acids is maintained in the  peptide chain is known as edmann degradation. this process includes the labelling of terminal amino residue  followed by the cleavage of this terminal amino residue from the peptide chain. the peptide bonds between other amino acids do not get disturb during this process.

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Chapter 24 Solutions

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