To write the mechanism of the last step in Gabriel amine synthesis, the basepromoted hydrolysis of a phthalimide to yield an amine plus phthalate ion. Concept introduction: An imide (-CoNHCo-) is similar to a Î²- keto ester, in that the acidic N-H hydrogen is flanked by two carbonyl groups.

Question

Want to see the full answer?

Answer 1

Question

Chapter 24.6, Problem 9P

Interpretation Introduction

Interpretation:

To write the mechanism of the last step in Gabriel amine synthesis, the basepromoted hydrolysis of a phthalimide to yield an amine plus phthalate ion.

Concept introduction:

An imide (-CoNHCo-) is similar to a Î²- keto ester, in that the acidic N-H hydrogen is flanked by two carbonyl groups.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Complete the reaction in the fewest number of steps as possible, Draw all intermediates (In the same form as the picture provided) and provide all reagents.

Please provide steps to work for complete understanding.

Answer 2

Question

Chapter 24.6, Problem 9P

Interpretation Introduction

Interpretation:

To write the mechanism of the last step in Gabriel amine synthesis, the basepromoted hydrolysis of a phthalimide to yield an amine plus phthalate ion.

Concept introduction:

An imide (-CoNHCo-) is similar to a Î²- keto ester, in that the acidic N-H hydrogen is flanked by two carbonyl groups.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Chapter 24.6, Problem 9P

Interpretation Introduction

Interpretation:

To write the mechanism of the last step in Gabriel amine synthesis, the basepromoted hydrolysis of a phthalimide to yield an amine plus phthalate ion.

Concept introduction:

An imide (-CoNHCo-) is similar to a Î²- keto ester, in that the acidic N-H hydrogen is flanked by two carbonyl groups.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Chapter 24.6, Problem 9P

Interpretation Introduction

Interpretation:

To write the mechanism of the last step in Gabriel amine synthesis, the basepromoted hydrolysis of a phthalimide to yield an amine plus phthalate ion.

Concept introduction:

An imide (-CoNHCo-) is similar to a Î²- keto ester, in that the acidic N-H hydrogen is flanked by two carbonyl groups.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 5

Chapter 24.6, Problem 9P

Interpretation Introduction

Interpretation:

To write the mechanism of the last step in Gabriel amine synthesis, the basepromoted hydrolysis of a phthalimide to yield an amine plus phthalate ion.

Concept introduction:

An imide (-CoNHCo-) is similar to a Î²- keto ester, in that the acidic N-H hydrogen is flanked by two carbonyl groups.

Answer 6

Chapter 24.6, Problem 9P

Interpretation Introduction

Interpretation:

To write the mechanism of the last step in Gabriel amine synthesis, the basepromoted hydrolysis of a phthalimide to yield an amine plus phthalate ion.

Concept introduction:

An imide (-CoNHCo-) is similar to a Î²- keto ester, in that the acidic N-H hydrogen is flanked by two carbonyl groups.

Answer 7

Chapter 24.6, Problem 9P

Interpretation Introduction

Interpretation:

To write the mechanism of the last step in Gabriel amine synthesis, the basepromoted hydrolysis of a phthalimide to yield an amine plus phthalate ion.

Concept introduction:

An imide (-CoNHCo-) is similar to a Î²- keto ester, in that the acidic N-H hydrogen is flanked by two carbonyl groups.

Answer 8

Expert Solution & Answer

Answer 9

Expert Solution & Answer

Answer 10

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 11

Ch. 24.1 - Name the following compounds:Ch. 24.1 - Prob. 2P Ch. 24.1 - Prob. 3P Ch. 24.3 - Prob. 4P Ch. 24.3 - The benzylammonium ion (C6H5CH2NH3+) has pKa =...Ch. 24.4 - Prob. 6P Ch. 24.5 - Prob. 7P Ch. 24.6 - Prob. 8P Ch. 24.6 - Prob. 9P Ch. 24.6 - Show two methods for the synthesis of dopamine, a...

To write the mechanism of the last step in Gabriel amine synthesis, the basepromoted hydrolysis of a phthalimide to yield an amine plus phthalate ion. Concept introduction: An imide (-CoNHCo-) is similar to a Î²- keto ester, in that the acidic N-H hydrogen is flanked by two carbonyl groups.

Solution Summary: The author explains the mechanism of the last step in Gabriel's amine synthesis, which is the base-promoted hydrolysis of a phthalimide.

Want to see the full answer?

Chapter 24 Solutions