2 SEM ACC W/RAVEN CARDED
2 SEM ACC W/RAVEN CARDED
12th Edition
ISBN: 9781264439218
Author: Raven
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Chapter 24.5, Problem 2LO
Summary Introduction

To determine: The method by which comparative genomics between pathogen and host can aid in drug development.

Introduction: An organism that is known to cause diseaseis called a pathogen and its tendency to cause diseaseis known as pathogenicity. A pathogen that invades and survives inside a host has some characteristics that are distinguishable from the non-pathogenic organisms. The pathogenicity can be enhanced due to the presence of locomotory organs.

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Alleles at the P locus control seed color. Plants which are pp have white seeds, white flowers and no pigment in vegetative parts. Plants which are P_ have black seeds, purple flowers and may have varying degrees of pigment on stems and leaves. Seed color can be assessed, visually, based on if the seed is white or not white A gene for mold resistance has been reported and we want to determine its inheritance and whether it is linked to P. For the purposes of this exercise, we will assume that resistance is controlled by a single locus M, and M_ plants are resistant and mm plants are susceptible.  Resistance can be measured, under greenhouse conditions, 2 weeks after planting, by injecting each seedling with a spore suspension. After two weeks, the seedlings can be rated as resistant or susceptible, based on whether or not tissue is actively sporulating. For this exercise we will use seed and data from the F10 generation of a recombinant inbred population produced using single seed…
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