The way by which the proteins constrain its DNA to allow supercoiling during single-stranded nicking. Concept introduction: Different types of DNA structures depend on the cell type. They include - closed circular, nicked circular and linear DNA. In closed circular DNA, the linear form of DNA is ligated using enzyme called as ligase, whereas the nicked DNA is an open circular DNA, which has a nick in it. Bacterial chromosome structure is composed of compact DNA structure that is supercoiled to form an intact structure. Over-winding or under-winding of strands gives DNA supercoils. However, a nick in the strand closes down the supercoiled structure of the DNA.

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Chapter 24, Problem 38CQ

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To explain: The way by which the proteins constrain its DNA to allow supercoiling during single-stranded nicking.

Concept introduction: Different types of DNA structures depend on the cell type. They include - closed circular, nicked circular and linear DNA. In closed circular DNA, the linear form of DNA is ligated using enzyme called as ligase, whereas the nicked DNA is an open circular DNA, which has a nick in it. Bacterial chromosome structure is composed of compact DNA structure that is supercoiled to form an intact structure. Over-winding or under-winding of strands gives DNA supercoils. However, a nick in the strand closes down the supercoiled structure of the DNA.

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