LooseLeaf for Human Anatomy
LooseLeaf for Human Anatomy
5th Edition
ISBN: 9781259285271
Author: Michael McKinley Dr., Valerie O'Loughlin, Elizabeth Pennefather-O'Brien
Publisher: McGraw-Hill Education
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Chapter 24, Problem 2DCR
Summary Introduction

To determine:

The cells that are infected during HIV infection, explaining the inability of the body to produce new mature cells, along with giving reasons that make HIV infection devastating to the body.

Introduction:

HIV stands for “human immunodeficiency virus.” This virus affects the body’s immune response, making it prone to other infections. The incubation period of HIV is usually very long, extending in years. In some cases, it can also extend upto ten years.

Summary Introduction

To explain:

The effect of AIDS on the body’s ability to fight infection, giving examples of ailments that are common in AIDS patients.

Introduction:

HIV infection leads to a condition where the patient’s body becomes deficient of the immune system. This stage is called “Acquired Immuno-deficiency Syndrome.” HIVs infects the cells of the immune system and reduce their ability to fight against other pathogens.

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A sample of blood was taken from the above individual and prepared for haemoglobin analysis. However, when water was added the cells did not lyse and looked normal in size and shape. The technician suspected that they had may have made an error in the protocol – what is the most likely explanation?   The cell membranes are more resistant than normal.   An isotonic solution had been added instead of water.   A solution of 0.1 M NaCl had been added instead of water.   Not enough water had been added to the red blood cell pellet.   The man had sickle-cell anaemia.
A sample of blood was taken from the above individual and prepared for haemoglobin analysis. However, when water was added the cells did not lyse and looked normal in size and shape. The technician suspected that they had may have made an error in the protocol – what is the most likely explanation?   The cell membranes are more resistant than normal.   An isotonic solution had been added instead of water.   A solution of 0.1 M NaCl had been added instead of water.   Not enough water had been added to the red blood cell pellet.   The man had sickle-cell anaemia.
With reference to their absorption spectra of the oxy haemoglobin intact line) and deoxyhemoglobin (broken line) shown in Figure 2 below, how would you best explain the reason why there are differences in the major peaks of the spectra? Figure 2. SPECTRA OF OXYGENATED AND DEOXYGENATED HAEMOGLOBIN OBTAINED WITH THE RECORDING SPECTROPHOTOMETER 1.4 Abs < 0.8 06 0.4 400 420 440 460 480 500 520 540 560 580 600 nm 1. The difference in the spectra is due to a pH change in the deoxy-haemoglobin due to uptake of CO2- 2. There is more oxygen-carrying plasma in the oxy-haemoglobin sample. 3. The change in Mr due to oxygen binding causes the oxy haemoglobin to have a higher absorbance peak. 4. Oxy-haemoglobin is contaminated by carbaminohemoglobin, and therefore has a higher absorbance peak 5. Oxy-haemoglobin absorbs more light of blue wavelengths and less of red wavelengths than deoxy-haemoglobin
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