The basic and non-basic nitrogen atoms of the histidine heterocycle. Interpretation: The basic and non-basic nitrogen atoms of the histidine heterocycle are to be predicted. Concept introduction: An amino acid that consists of α − amino group, a carboxylic group and an imidazole side chain is known as Histidine. It is used in the biosynthesis of proteins and acts as a significant catalytic residue that is found at the active sites of many enzyme. Histidine appears to remove protons or it might be used to transfer protons from one location to another.

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Answer 1

Question

Chapter 24, Problem 24.41SP

(a)

Interpretation Introduction

To determine: The basic and non-basic nitrogen atoms of the histidine heterocycle.

Interpretation: The basic and non-basic nitrogen atoms of the histidine heterocycle are to be predicted.

Concept introduction: An amino acid that consists of α−amino group, a carboxylic group and an imidazole side chain is known as Histidine. It is used in the biosynthesis of proteins and acts as a significant catalytic residue that is found at the active sites of many enzyme. Histidine appears to remove protons or it might be used to transfer protons from one location to another.

(b)

Interpretation Introduction

To determine: The reason corresponding to the fact that the protonated form of histidine is a particularly stable cation with help of resonance forms.

Interpretation: The reason corresponding to the fact that the protonated form of histidine is a particularly stable cation with help of resonance forms are to be predicted.

Concept introduction: An amino acid that consists of α−amino group, a carboxylic group and an imidazole side chain is known as Histidine. It is used in the biosynthesis of proteins and acts as a significant catalytic residue that is found at the active sites of many enzyme. Histidine appears to remove protons or it might be used to transfer protons from one location to another.

(c)

Interpretation Introduction

To determine: The structures of histidine that shows histidine accepts a proton on the basic nitrogen of the heterocycle and then get deprotonated on the other heterocyclic nitrogen and the explanation regarding the fact that the histidine might function as a pipeline to transfer protons between sites within an enzyme and its substrate.

Interpretation: The structures of histidine that shows histidine accepts a proton on the basic nitrogen of the heterocycle and then get deprotonated on the other heterocyclic nitrogen are to be shown and the explanation regarding the fact that histidine might function as a pipeline to transfer protons between sites within an enzyme and its substrate is to be stated.

Concept introduction: An amino acid that consists of α−amino group, a carboxylic group and an imidazole side chain is known as Histidine. It is used in the biosynthesis of proteins and acts as a significant catalytic residue that is found at the active sites of many enzyme. Histidine appears to remove protons or it might be used to transfer protons from one location to another.

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Answer 2

Question

Chapter 24, Problem 24.41SP

(a)

Interpretation Introduction

To determine: The basic and non-basic nitrogen atoms of the histidine heterocycle.

Interpretation: The basic and non-basic nitrogen atoms of the histidine heterocycle are to be predicted.

Concept introduction: An amino acid that consists of α−amino group, a carboxylic group and an imidazole side chain is known as Histidine. It is used in the biosynthesis of proteins and acts as a significant catalytic residue that is found at the active sites of many enzyme. Histidine appears to remove protons or it might be used to transfer protons from one location to another.

(b)

Interpretation Introduction

To determine: The reason corresponding to the fact that the protonated form of histidine is a particularly stable cation with help of resonance forms.

Interpretation: The reason corresponding to the fact that the protonated form of histidine is a particularly stable cation with help of resonance forms are to be predicted.

Concept introduction: An amino acid that consists of α−amino group, a carboxylic group and an imidazole side chain is known as Histidine. It is used in the biosynthesis of proteins and acts as a significant catalytic residue that is found at the active sites of many enzyme. Histidine appears to remove protons or it might be used to transfer protons from one location to another.

(c)

Interpretation Introduction

To determine: The structures of histidine that shows histidine accepts a proton on the basic nitrogen of the heterocycle and then get deprotonated on the other heterocyclic nitrogen and the explanation regarding the fact that the histidine might function as a pipeline to transfer protons between sites within an enzyme and its substrate.

Interpretation: The structures of histidine that shows histidine accepts a proton on the basic nitrogen of the heterocycle and then get deprotonated on the other heterocyclic nitrogen are to be shown and the explanation regarding the fact that histidine might function as a pipeline to transfer protons between sites within an enzyme and its substrate is to be stated.

Concept introduction: An amino acid that consists of α−amino group, a carboxylic group and an imidazole side chain is known as Histidine. It is used in the biosynthesis of proteins and acts as a significant catalytic residue that is found at the active sites of many enzyme. Histidine appears to remove protons or it might be used to transfer protons from one location to another.

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Answer 3

Question

Chapter 24, Problem 24.41SP

(a)

Interpretation Introduction

To determine: The basic and non-basic nitrogen atoms of the histidine heterocycle.

Interpretation: The basic and non-basic nitrogen atoms of the histidine heterocycle are to be predicted.

Concept introduction: An amino acid that consists of α−amino group, a carboxylic group and an imidazole side chain is known as Histidine. It is used in the biosynthesis of proteins and acts as a significant catalytic residue that is found at the active sites of many enzyme. Histidine appears to remove protons or it might be used to transfer protons from one location to another.

(b)

Interpretation Introduction

To determine: The reason corresponding to the fact that the protonated form of histidine is a particularly stable cation with help of resonance forms.

Interpretation: The reason corresponding to the fact that the protonated form of histidine is a particularly stable cation with help of resonance forms are to be predicted.

Concept introduction: An amino acid that consists of α−amino group, a carboxylic group and an imidazole side chain is known as Histidine. It is used in the biosynthesis of proteins and acts as a significant catalytic residue that is found at the active sites of many enzyme. Histidine appears to remove protons or it might be used to transfer protons from one location to another.

(c)

Interpretation Introduction

To determine: The structures of histidine that shows histidine accepts a proton on the basic nitrogen of the heterocycle and then get deprotonated on the other heterocyclic nitrogen and the explanation regarding the fact that the histidine might function as a pipeline to transfer protons between sites within an enzyme and its substrate.

Interpretation: The structures of histidine that shows histidine accepts a proton on the basic nitrogen of the heterocycle and then get deprotonated on the other heterocyclic nitrogen are to be shown and the explanation regarding the fact that histidine might function as a pipeline to transfer protons between sites within an enzyme and its substrate is to be stated.

Concept introduction: An amino acid that consists of α−amino group, a carboxylic group and an imidazole side chain is known as Histidine. It is used in the biosynthesis of proteins and acts as a significant catalytic residue that is found at the active sites of many enzyme. Histidine appears to remove protons or it might be used to transfer protons from one location to another.

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Answer 4

Question

Chapter 24, Problem 24.41SP

(a)

Interpretation Introduction

To determine: The basic and non-basic nitrogen atoms of the histidine heterocycle.

Interpretation: The basic and non-basic nitrogen atoms of the histidine heterocycle are to be predicted.

Concept introduction: An amino acid that consists of α−amino group, a carboxylic group and an imidazole side chain is known as Histidine. It is used in the biosynthesis of proteins and acts as a significant catalytic residue that is found at the active sites of many enzyme. Histidine appears to remove protons or it might be used to transfer protons from one location to another.

(b)

Interpretation Introduction

To determine: The reason corresponding to the fact that the protonated form of histidine is a particularly stable cation with help of resonance forms.

Interpretation: The reason corresponding to the fact that the protonated form of histidine is a particularly stable cation with help of resonance forms are to be predicted.

Concept introduction: An amino acid that consists of α−amino group, a carboxylic group and an imidazole side chain is known as Histidine. It is used in the biosynthesis of proteins and acts as a significant catalytic residue that is found at the active sites of many enzyme. Histidine appears to remove protons or it might be used to transfer protons from one location to another.

(c)

Interpretation Introduction

To determine: The structures of histidine that shows histidine accepts a proton on the basic nitrogen of the heterocycle and then get deprotonated on the other heterocyclic nitrogen and the explanation regarding the fact that the histidine might function as a pipeline to transfer protons between sites within an enzyme and its substrate.

Interpretation: The structures of histidine that shows histidine accepts a proton on the basic nitrogen of the heterocycle and then get deprotonated on the other heterocyclic nitrogen are to be shown and the explanation regarding the fact that histidine might function as a pipeline to transfer protons between sites within an enzyme and its substrate is to be stated.

Concept introduction: An amino acid that consists of α−amino group, a carboxylic group and an imidazole side chain is known as Histidine. It is used in the biosynthesis of proteins and acts as a significant catalytic residue that is found at the active sites of many enzyme. Histidine appears to remove protons or it might be used to transfer protons from one location to another.

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Answer 5

Chapter 24, Problem 24.41SP

(a)

Interpretation Introduction

To determine: The basic and non-basic nitrogen atoms of the histidine heterocycle.

Interpretation: The basic and non-basic nitrogen atoms of the histidine heterocycle are to be predicted.

Concept introduction: An amino acid that consists of α−amino group, a carboxylic group and an imidazole side chain is known as Histidine. It is used in the biosynthesis of proteins and acts as a significant catalytic residue that is found at the active sites of many enzyme. Histidine appears to remove protons or it might be used to transfer protons from one location to another.

(b)

Interpretation Introduction

To determine: The reason corresponding to the fact that the protonated form of histidine is a particularly stable cation with help of resonance forms.

Interpretation: The reason corresponding to the fact that the protonated form of histidine is a particularly stable cation with help of resonance forms are to be predicted.

Concept introduction: An amino acid that consists of α−amino group, a carboxylic group and an imidazole side chain is known as Histidine. It is used in the biosynthesis of proteins and acts as a significant catalytic residue that is found at the active sites of many enzyme. Histidine appears to remove protons or it might be used to transfer protons from one location to another.

(c)

Interpretation Introduction

To determine: The structures of histidine that shows histidine accepts a proton on the basic nitrogen of the heterocycle and then get deprotonated on the other heterocyclic nitrogen and the explanation regarding the fact that the histidine might function as a pipeline to transfer protons between sites within an enzyme and its substrate.

Interpretation: The structures of histidine that shows histidine accepts a proton on the basic nitrogen of the heterocycle and then get deprotonated on the other heterocyclic nitrogen are to be shown and the explanation regarding the fact that histidine might function as a pipeline to transfer protons between sites within an enzyme and its substrate is to be stated.

Concept introduction: An amino acid that consists of α−amino group, a carboxylic group and an imidazole side chain is known as Histidine. It is used in the biosynthesis of proteins and acts as a significant catalytic residue that is found at the active sites of many enzyme. Histidine appears to remove protons or it might be used to transfer protons from one location to another.

Answer 6

Chapter 24, Problem 24.41SP

(a)

Interpretation Introduction

To determine: The basic and non-basic nitrogen atoms of the histidine heterocycle.

Interpretation: The basic and non-basic nitrogen atoms of the histidine heterocycle are to be predicted.

Concept introduction: An amino acid that consists of α−amino group, a carboxylic group and an imidazole side chain is known as Histidine. It is used in the biosynthesis of proteins and acts as a significant catalytic residue that is found at the active sites of many enzyme. Histidine appears to remove protons or it might be used to transfer protons from one location to another.

Answer 7

Chapter 24, Problem 24.41SP

(a)

Interpretation Introduction

To determine: The basic and non-basic nitrogen atoms of the histidine heterocycle.

Interpretation: The basic and non-basic nitrogen atoms of the histidine heterocycle are to be predicted.

Concept introduction: An amino acid that consists of α−amino group, a carboxylic group and an imidazole side chain is known as Histidine. It is used in the biosynthesis of proteins and acts as a significant catalytic residue that is found at the active sites of many enzyme. Histidine appears to remove protons or it might be used to transfer protons from one location to another.

Answer 8

(b)

Interpretation Introduction

To determine: The reason corresponding to the fact that the protonated form of histidine is a particularly stable cation with help of resonance forms.

Interpretation: The reason corresponding to the fact that the protonated form of histidine is a particularly stable cation with help of resonance forms are to be predicted.

Concept introduction: An amino acid that consists of α−amino group, a carboxylic group and an imidazole side chain is known as Histidine. It is used in the biosynthesis of proteins and acts as a significant catalytic residue that is found at the active sites of many enzyme. Histidine appears to remove protons or it might be used to transfer protons from one location to another.

Answer 9

(b)

Interpretation Introduction

To determine: The reason corresponding to the fact that the protonated form of histidine is a particularly stable cation with help of resonance forms.

Interpretation: The reason corresponding to the fact that the protonated form of histidine is a particularly stable cation with help of resonance forms are to be predicted.

Concept introduction: An amino acid that consists of α−amino group, a carboxylic group and an imidazole side chain is known as Histidine. It is used in the biosynthesis of proteins and acts as a significant catalytic residue that is found at the active sites of many enzyme. Histidine appears to remove protons or it might be used to transfer protons from one location to another.

Answer 10

(c)

Interpretation Introduction

To determine: The structures of histidine that shows histidine accepts a proton on the basic nitrogen of the heterocycle and then get deprotonated on the other heterocyclic nitrogen and the explanation regarding the fact that the histidine might function as a pipeline to transfer protons between sites within an enzyme and its substrate.

Interpretation: The structures of histidine that shows histidine accepts a proton on the basic nitrogen of the heterocycle and then get deprotonated on the other heterocyclic nitrogen are to be shown and the explanation regarding the fact that histidine might function as a pipeline to transfer protons between sites within an enzyme and its substrate is to be stated.

Concept introduction: An amino acid that consists of α−amino group, a carboxylic group and an imidazole side chain is known as Histidine. It is used in the biosynthesis of proteins and acts as a significant catalytic residue that is found at the active sites of many enzyme. Histidine appears to remove protons or it might be used to transfer protons from one location to another.

Answer 11

(c)

Interpretation Introduction

To determine: The structures of histidine that shows histidine accepts a proton on the basic nitrogen of the heterocycle and then get deprotonated on the other heterocyclic nitrogen and the explanation regarding the fact that the histidine might function as a pipeline to transfer protons between sites within an enzyme and its substrate.

Interpretation: The structures of histidine that shows histidine accepts a proton on the basic nitrogen of the heterocycle and then get deprotonated on the other heterocyclic nitrogen are to be shown and the explanation regarding the fact that histidine might function as a pipeline to transfer protons between sites within an enzyme and its substrate is to be stated.

Concept introduction: An amino acid that consists of α−amino group, a carboxylic group and an imidazole side chain is known as Histidine. It is used in the biosynthesis of proteins and acts as a significant catalytic residue that is found at the active sites of many enzyme. Histidine appears to remove protons or it might be used to transfer protons from one location to another.

Answer 12

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Answer 15

Ch. 24.2A - Draw three-dimensional representations of the...Ch. 24.2A - Prob. 24.2P Ch. 24.2B - The herbicide glyphosate (Roundup) kills plants by...Ch. 24.4 - Draw the structure of the predominant form of a....Ch. 24.4 - Draw the resonance forms of a protonated guanidino...Ch. 24.4 - Although tryptophan contains a heterocyclic amine,...Ch. 24.4 - Prob. 24.7P Ch. 24.4 - Prob. 24.8P Ch. 24.5A - Show how the following amino acids might be formed...Ch. 24.5B - Prob. 24.10P

Solution Summary: The author explains the basic and non-basic nitrogen atoms of the histidine heterocycle.

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