Genetics: Analysis and Principles
5th Edition
ISBN: 9780073525341
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 24, Problem 22CONQ
Summary Introduction
To review:
The proto-oncogene and function of the protein encoded by them. The methods by which the proto-oncogenes are converted into oncogenes.
Introduction:
Cancer cells are cells thatgrow uncontrollably. Cancer cells have lost their properties of contact inhibition and density-dependent inhibition which, allows cells to grow in multiple layersand spread to other body parts. The conversion of proto-oncogenes into oncogenes enhances the proliferation of cells due to a mutation within the genes which, eventually causes cancer.
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Transcription and Translation
1. What is the main function of transcription and translation? (2
marks)
2. How is transcription different in eukaryotic and prokaryotic
cells? (2 marks)
3. Explain the difference between pre-mRNA and post-transcript
mRNA. (2 marks)
4. What is the function of the following: (4 marks)
i. the cap
ii. spliceosome
iii. Poly A tail
iv. termination sequence
5. What are advantages to the wobble feature of the genetic
code? (2 marks)
6. Explain the difference between the: (3 marks)
i. A site & P site
ii. codon & anticodon
iii. gene expression and gene regulation
7. Explain how the stop codon allows for termination. (1 mark)
8. In your own words, summarize the process of translation. (2
marks)
Chapter 24 Solutions
Genetics: Analysis and Principles
Ch. 24.1 - Which of the following wouldnotbe consistent with...Ch. 24.1 - 2. Assuming complete penetrance, which type of...Ch. 24.1 - 3. Which of the following is not a common...Ch. 24.1 - Prob. 4COMQCh. 24.2 - Prob. 1COMQCh. 24.2 - Haplotype association studies are aimed at the...Ch. 24.3 - 1. Which of the following is not a method used in...Ch. 24.3 - 2. Which of the following prenatal genetic testing...Ch. 24.4 - Prob. 1COMQCh. 24.5 - 1. An oncogene is produced from a ________that has...
Ch. 24.5 - Which of the following is a type of genetic change...Ch. 24.5 - 3. Tumor-suppressor genes promote cancer...Ch. 24.5 - 4. Normal (nonmutant) tumor-suppressor genes often...Ch. 24.5 - Prob. 5COMQCh. 24.6 - Prob. 1COMQCh. 24 - 1. With regard to pedigree analysis, make a list...Ch. 24 - 2. Explain, at the molecular level, why human...Ch. 24 - 3. Many genetic disorders exhibit locus...Ch. 24 - Prob. 4CONQCh. 24 - Prob. 5CONQCh. 24 - Figure 25.1 illustrates albinism in two different...Ch. 24 - Prob. 7CONQCh. 24 - Prob. 8CONQCh. 24 - Ehler-Danlos syndrome is a rare disorder caused by...Ch. 24 - 10. Hurler syndrome is due to a mutation in a gene...Ch. 24 - Like Hurler syndrome, Fabry disease involves an...Ch. 24 - Achondroplasia is a rare form of dwarfism caused...Ch. 24 - Prob. 13CONQCh. 24 - 14. Marfan syndrome is due to a mutation in a...Ch. 24 - 15. Sandhoff disease is due to a mutation in a...Ch. 24 - Describe the two assumptions that underlie the...Ch. 24 - Prob. 17CONQCh. 24 - What is a prion? Explain how a prion relies on...Ch. 24 - 19. Some people have a genetic predisposition for...Ch. 24 - What is the difference between an oncogene and a...Ch. 24 - C20. Familial fatal insomnia (described in Table)...Ch. 24 - Prob. 22CONQCh. 24 - Prob. 23CONQCh. 24 - Prob. 24CONQCh. 24 - Prob. 25CONQCh. 24 - Prob. 26CONQCh. 24 - Prob. 27CONQCh. 24 - Prob. 28CONQCh. 24 - With regard to cancer cells, which of the...Ch. 24 - Prob. 30CONQCh. 24 - 1. Which of the following experimental...Ch. 24 - Prob. 2EQCh. 24 - 3. What is meant by the term genetic testing? How...Ch. 24 - Prob. 4EQCh. 24 - 5. Chapter 21 describes a method known as Western...Ch. 24 - 6. An experimental assay for the blood-clotting...Ch. 24 - 7. Discuss ways to distinguish whether a...Ch. 24 - 8. The codon change (Gly-12 to Val-12) in...Ch. 24 - Explain how DNA microarrays are used in molecular...Ch. 24 - E7. Lets suppose a cell line has become malignant...Ch. 24 - Prob. 8EQCh. 24 - Prob. 9EQCh. 24 - Prob. 10EQCh. 24 - Prob. 13EQCh. 24 - Make a list of the benefits that may arise from...Ch. 24 - Our government has finite funds to devote to...
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