EBK BIOLOGY: CONCEPTS AND APPLICATIONS
9th Edition
ISBN: 9780100477803
Author: STARR
Publisher: YUZU
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Chapter 24, Problem 1CT
Researchers recently compared mitochondrial DNA from a fossil finger found in Siberia to mitochondrial DNA (mitoDNA) from modern humans. The sequence of the finger DNA differed from modern human DNA at an average of 385 sites. Neanderthal mitoDNA differs from modern human mitoDNA at an average of 202 sites, and chimpanzee mitoDNA differs from human mitoDNA at an average of 1, 462 sites. Using this information, draw a tree that shows the relationship between chimpanzees, humans, Neanderthals, and the owner of this finger.
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Kinetics: One-Compartment First-Order Absorption
1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple routes of administration provides greater insight than a single route of administration alone. The following data was collected in 250-g rats following bolus IV, oral (PO), and intraperitoneal (ip) administration.
Using this data and set of graphs, determine:(calculate for each variable)
(a) k, C0, V, and AUC* for the bolus iv data
(b) k, ka, B1, and AUC* for the po data
c) k, ka, B1, and AUC* for the ip data
(d) relative bioavailability for po vs ip, Fpo/Fip
(e)absolute ip bioavailability, Fip
(f) absolute po bioavailability, Fpo
Chapter 24 Solutions
EBK BIOLOGY: CONCEPTS AND APPLICATIONS
Ch. 24 - Prob. 1SQCh. 24 - Prob. 2SQCh. 24 - Vertebrate jaws evolved from _______. a. gill...Ch. 24 - Prob. 4SQCh. 24 - A divergence from ________ gave rise to tetrapods....Ch. 24 - Reptiles, including birds, belong to one major...Ch. 24 - Reptiles are adapted to life on land by ______. a....Ch. 24 - The closest modern relatives of birds are...Ch. 24 - The defining trait of hominins is __________. a....Ch. 24 - Among living animals, only birds have ________. a....
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