Human Anatomy & Physiology Plus Mastering A&P with Pearson eText -- Access Card Package (2nd Edition) (What's New in Anatomy & Physiology)
2nd Edition
ISBN: 9780134702339
Author: Erin C. Amerman
Publisher: PEARSON
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Chapter 24, Problem 1AYKA
Drugs that treat hypertension, or high blood pressure, have the following actions. Discuss the specific effect that each drug will have on the kidneys.
a. Blocking the action of aldosterone on the kidneys
b. Blocking the receptor for angiotensin-II on blood vessels and in the renal tubule cells
c. Blocking the
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The result of renal autoregulation is(are):
A. Minimize loss of water in urine after an increase of cardiac output
B. Minimize decrease of ECF after an increase of cardiac output
C. Minimize effect of increased systemic pressure on urine output
OD. Minimize loss of sodium in urine after an increase of cardiac output
OE. All of the above
The renal handling of a novel drug is being studied. When the drug is present in the blood, it is filtered into the Bowman’s capsule and secreted via transport proteins in the renal tubules, but it is NOT reabsorbed. The lines on the following graph represent filtration, secretion and excretion rates of this drug at various plasma concentrations.
For the three lines shown (labeled A-C) identify which line represents filtration, which line represents secretion, and which line represents excretion
Explain how you determined this.
Which of the following is TRUE concerning renal handling of potassium?
a.
A high potassium meal will cause enhanced basolateral uptake via sodium-potassium pumps
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Most potassium reabsorption occurs at the distal tubules
c.
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d.
Potassium is not filtered, so urinary excretion of potassium will only occur by stimulating potassium secretion
e.
Decreased extracellular potassium concentration increases aldosterone production and thereby reduces potassium secretion
Chapter 24 Solutions
Human Anatomy & Physiology Plus Mastering A&P with Pearson eText -- Access Card Package (2nd Edition) (What's New in Anatomy & Physiology)
Ch. 24.1 - What are the organs of the urinary system?Ch. 24.1 - 2. What are the basic functions of the kidneys?
Ch. 24.2 - Prob. 1QCCh. 24.2 - 2. What are the three regions of the kidney, and...Ch. 24.2 - Prob. 3QCCh. 24.2 - Trace the sequence of blood flow through the...Ch. 24.2 - Prob. 5QCCh. 24.2 - Prob. 6QCCh. 24.2 - Trace the pathway filtrate takes through the...Ch. 24.3 - Prob. 1QC
Ch. 24.3 - 2. How do tubular reabsorption and tubular...Ch. 24.4 - Prob. 1QCCh. 24.4 - Prob. 2QCCh. 24.4 - Prob. 3QCCh. 24.4 - 4. What is the GFR?
Ch. 24.4 - Prob. 5QCCh. 24.4 - Prob. 6QCCh. 24.4 - 7. How does tubuloglomerular feedback affect the...Ch. 24.4 - Prob. 8QCCh. 24.4 - Prob. 9QCCh. 24.4 - Prob. 10QCCh. 24.4 - How does the sympathetic nervous system affect the...Ch. 24.5 - Prob. 1QCCh. 24.5 - 2. What are the three types of transport...Ch. 24.5 - Prob. 3QCCh. 24.5 - What is obligatory water reabsorption?Ch. 24.5 - How do the permeabilities of the two limbs of the...Ch. 24.5 - Prob. 6QCCh. 24.5 - Prob. 7QCCh. 24.5 - Prob. 8QCCh. 24.6 - Prob. 1QCCh. 24.6 - Prob. 2QCCh. 24.6 - Prob. 3QCCh. 24.6 - Prob. 4QCCh. 24.6 - 5. What three factors allow the kidney to produce...Ch. 24.6 - 6. How is concentrated urine produced?
Ch. 24.8 - 1. What is the normal composition of urine?
Ch. 24.8 - Prob. 2QCCh. 24.8 - 3. What is renal clearance, and what is it used...Ch. 24.9 - Prob. 1QCCh. 24.9 - 2. What are the functions of the ureters and...Ch. 24.9 - Prob. 3QCCh. 24.9 - Prob. 4QCCh. 24.9 - Prob. 5QCCh. 24 - What are the four main organs of the urinary...Ch. 24 - 2. Which of the following is not a physiological...Ch. 24 - Mark the following statements as true or false. If...Ch. 24 - Prob. 4CYRCh. 24 - Prob. 5CYRCh. 24 - Which of the following substances would pass...Ch. 24 - Mark the following statements as true or false. If...Ch. 24 - Fill in the blanks for the following statements:...Ch. 24 - Which of the following is false about the GFR? a....Ch. 24 - The route by which substances are reabsorbed by...Ch. 24 - 11. Fill in the blanks: Glomerular hydrostatic...Ch. 24 - Dilute urine is produced when decreased levels of...Ch. 24 - Prob. 13CYRCh. 24 - Prob. 14CYRCh. 24 - Prob. 15CYRCh. 24 - 16. The GFR may be estimated by measuring the rate...Ch. 24 - Prob. 17CYRCh. 24 - Prob. 1CYUCh. 24 - Prob. 2CYUCh. 24 - Prob. 3CYUCh. 24 - Why must the kidneys establish a concentration...Ch. 24 - 1. Drugs that treat hypertension, or high blood...Ch. 24 - Prob. 2AYKACh. 24 - 3. Deana is a 4-year-old girl with a rare genetic...Ch. 24 - 4. Explain how each of the drugs in question 1...Ch. 24 - 5. What might it mean if you found a high...
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- Which of the following does not contribute to the high salt concentration in the interstitial fluid of the kidney medulla? (a) active transport of sodium from the upper part of the ascending limb (b) diffusion of salt from the ascending limb of the loop of Henle (c) reabsorption of salt from various regions of Bowmans capsule (d) counterflow of fluid through the two limbs of the loop of Henle (e) diffusion of urea out of the collecting ductarrow_forwardWhich of the following is an example of autoregulation of kidney function? a. The RAAS regulates Na1 by secreting renin when blood pressure or blood volume decreases. b. The ADH system regulates water balance by decreasing water reabsorption and increasing excretion of salt. c. Receptors in the juxtaglomerular apparatus detect a higher salt concentration in the distal convoluted tubule and trigger constriction of the afferent arteriole to reduce glomerular filtration rate. d. ANF is released by the kidney to increase renin release. e. Angiotensin II lowers blood pressure by constricting arterioles.arrow_forwardFigure 41.8 Loop diuretics are drugs sometimes used to treat hypertension. These drugs inhibit the reabsorption of Na+ and Cl- ions by the ascending limb of the loop of Henle. A side effect is that they increase urination. Why do you think this is the case?arrow_forward
- As the text noted, two-thirds of the water and solutes that the body reclaims by reabsorption in nephrons occurs in the proximal tubule. Proximal tubule cells have large numbers of mitochondria and demand a great deal of oxygen. Explain why.arrow_forwardFatty tissue holds the kidneys in place. Extremely rapid weight loss may cause this tissue to shrink so that the kidneys slip from their normal position. On rare occasions, the slippage can put a kink in one or both ureters and block urine flow. Suggest what might then happen to the kidneys.arrow_forwardAn investigator is studying renal physiology in patients with type 1 diabetes mellitus. When a substance that inhibits glucose reabsorption is given, which of the following best describes the clearance of glucose?a. Decreases and approaches the clearance of p-aminohippurateb. Decreases and approaches the clearance of inulinC. Increases and approaches the clearance of p-aminohippurated. Increases and approaches the clearance of inuline. Increases and approaches the clearance of sodiumarrow_forward
- Which one of the following statements is false?a. Blood pressure in the glomerular capillaries is greater than the osmotic pressure exerted by proteins in the plasma within the glomerular capillaries.b. If the osmotic pressure exerted by solutes in the peritubular capillaries is greater than the blood pressure in those capillaries, then water will be reabsorbed.c. Endothelial cells in glomerular capillaries are highly permeable, facilitating filtration of fluid into Bowman’s capsule.d. Constriction of the afferent arteriole is likely to reduce the volume of filtrate appearing in Bowman’s capsule.e. The efferent arteriole carries blood from the glomerular capillaries directly to the renal vein.0.5 pointsQuestion 2Your doctor calls with the results of your urinalysis and tells you that they found proteinuria, the presence of abnormal amounts of protein in your urine sample. What could have caused this?a. Infection and inflammation in the kidney.b. Abnormally high concentration of plasma…arrow_forwardwould damage to the renal capillaries resulting in an increase in protein filtration and urinary tion affect net filtration pressure in the systemic circulation? Increase capillary reabsorption due to an increase in interstitial colloid osmotic pressure Increase capillary filtration due to an increase in interstitial hydrostatic pressure . Increase capillary filtration due to a decrease in blood colloid osmotic pressure 1. Increase capillary eabsorption due to increased blood hydrostatic pressurearrow_forward1. 3 of the following are true of the Renin Angiotensin Aldosterone System (RAAS) A. The JG cells are located at the distal collecting tubule B. The Juxtaglomerular cells (JG cells) are modified smooth muscles in the afferent arteriole C. The Macula densa detects osmolality of the filtrate D. The Macula densa is made up of tall columnar cells 2. 2 of the following are true of the RAAS responding to a decrease in Na in the filtrate A. Macula densa detects the decrease in osmolality B. JG cells are stimulated by Macula densa through tight junctions C. Aldosterone stimulates principal cells of collecting tubule to reabsorb water D. Aldosterone reabsorbs Na and by osmotic forces increase fluid in the extracellular compartment 3. 2 of the following are true of the loop of Henle A. Descending thick limb is also called the pars recta of the proximal tubule B. The function of the descending thick limb is similar to the distal convoluted tubule C. Cells of the descending thin limb are very…arrow_forward
- Atrial Natriuretic Peptide helps to reduce overall blood pressure in a variety of ways. One way is by increasing Glomerular Filtration Rate. a. Why/how would increasing GFR cause decreased blood pressure? b. To increase GFR, would Atrial Natriuretic Peptide cause constriction or dilation of afferent arterioles at the kidneys? The efferent arterioles?arrow_forwardThese vessels marked by the white arrow 1. are classified as 'cap bed 1' vessels in the renal portal system 2. function to secrete glucose molecules across the wall of the proximal convoluted tubule 3. move hydrogen ions across their endothelial cells into the lining cells of the proximal convoluted tubule for pH regulation (if the blood is in acidosis) 4. secrete the products of drugs metabolism into the filtrate of the proximal convoluted tubules Choose from the following: (A) 1 and 2 (B) 2 and 3 (C) 1 and 3 (D) 1, 2, and 3 (E) 3 only (F) 4 only (G) 1, 2, 3, and 4arrow_forwardWhich is the correct answer for kidney from the following statement(s)? Local production of prostaglandin in kidney protects kidney from ischemic injury. a. Sympathetic stimulation has no effect on afferent and efferent arterioles so that kidney is protected from undergoing ischemia. b. Kidney is vulnerable to ischemic injury. C. d. NSAID inhibits production of angiotensin I. Only (a) and (c) are CORRECT e.arrow_forward
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