BIO 212 HUMAN BIOLOGY LAB NOTEBOOK
16th Edition
ISBN: 9781307769883
Author: Mader
Publisher: MCG/CREATE
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Chapter 23.3, Problem 2QTC
Summary Introduction
To analyze:
The difficulty in using genetic engineering to modify a trait determined by multiple gene interactions.
Introduction:
Genetic engineering is being used these days to modify existing traits in organisms. An example is gene therapy where the faulty gene in the organism is replaced by the right gene, reversing the harmful
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 23 Solutions
BIO 212 HUMAN BIOLOGY LAB NOTEBOOK
Ch. 23.1 - Describe how Mendel's law of segregation and law...Ch. 23.1 - Define the term allele, and explain what it means...Ch. 23.1 - Contrast genotype and phenotype, and use...Ch. 23.1 - Predict outcome ratios and probabilities for...Ch. 23.1 - Prob. 1QTCCh. 23.1 - 2. Decide the reasons listed in the feature, what...Ch. 23.1 - Prob. 3QTCCh. 23.1 - Distinguish between the terms genotype and...Ch. 23.1 - Explain the purpose of testcross.Ch. 23.1 - Prob. 3CYP
Ch. 23.1 - Describe the types of process that result in a 3:1...Ch. 23.2 - Recognize autosomal dominant and autosomal...Ch. 23.2 - Analyze pedigree to determine the probability of a...Ch. 23.2 - Describe the characteristics of a Pedigree for an...Ch. 23.2 - Prob. 2CYPCh. 23.3 - Prob. 1LOCh. 23.3 - Prob. 2LOCh. 23.3 - Describe polygenic inheritance.Ch. 23.3 - What would be the potential consequences if one of...Ch. 23.3 - Prob. 2QTCCh. 23.3 - Prob. 1CYPCh. 23.3 - Prob. 2CYPCh. 23.4 - Prob. 1LOCh. 23.4 - Understand how scientists determine the effect of...Ch. 23.4 - Prob. 1CYPCh. 23.4 - Prob. 2CYPCh. 23 - Prob. C2BYBCh. 23 - Prob. S5.4BYBCh. 23 - Prob. S5.6BYBCh. 23 - The law of segregation states all of the following...Ch. 23 - Prob. 2ACh. 23 - Prob. 3ACh. 23 - Prob. 4ACh. 23 - Prob. 5ACh. 23 - Prob. 6ACh. 23 - Which of the following does not have an autosomal...Ch. 23 - 8. Which of the following does not describe the...Ch. 23 - Prob. 9ACh. 23 - Prob. 10ACh. 23 - Prob. 11ACh. 23 - Prob. 12ACh. 23 - Prob. 1TCCh. 23 - How would you determine whether a disease in...Ch. 23 - Prob. 3TC
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