Molecular Biology of the Cell (Sixth Edition)
6th Edition
ISBN: 9780815344322
Author: Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher: W. W. Norton & Company
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Chapter 23, Problem 9P
Summary Introduction
To explain: How YopJ block the TAK1 signaling pathway.
Introduction: YopJ is a serine/threonine kinase that acetylates the various MAP kinases including TAK1.
Summary Introduction
To explain: How suppose the serine/threonine acetylase activity of YopJ might interfare with TAK1 activation.
Introduction: Yersinia pestis is a gram negative bacterium that causes plague. Upon infection, the bacterium injects a set of effector proteins into macrophages. This suppresses their innate immune response. YopJ is a serine/threonine kinase that acetylates the various MAP kinases including TAK1.
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