Chapter 23, Problem 2P

For each DNA repair process in column I, list all characteristics from column Il that correctly describe that process.
I

1. Nucleotide excision repair
2. Photoreactivation
3. Base excision repair
4. Recombinational repair
5. SOS-driven error-prone repair
6. Alkyltransferase repair
7. Mismatch repair
8. Double-strand break repair

II

1. RecA protein participates.
2. Damaged nucleotides are removed by nick translation.
3. A free radical mechanism is involved.
4. The repair enzyme functions only once.
5. The key enzyme contains a bound folate cofactor.
6. No bases or nucleotides are removed from the DNA.
7. Deficiency of this enzyme in humans greatly increases the risk of skin cancer.
8. This system is chiefly responsible for the mutagenic effect of ultraviolet light.
9. This process begins with cleavage of two phosphodiester bonds.
10. This process begins up to 1 kbp away from the site to be repaired.
11. DNA ligase catalyzes the final reaction.
12. This process also occurs in meiotic recombination.
13. Replication fork regression might occur during this process.