If the deficiency of DAM (deoxyadenosine) methylase will decrease, increase or will have no effect on the mutation rates should be explained. Concept introduction: Deoxyadenosine methylase is commonly referred to as DAM methylase. This is an enzyme that catalyzes the addition of methyl ( CH 3 ) group to the adenine of the sequence of 5 ' − GATC − 3 ' in the DNA (Deoxyribonucleic acid) which is newly synthesized.

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Answer 1

Question

Chapter 23, Problem 1P

Interpretation Introduction

Interpretation:

If the deficiency of DAM (deoxyadenosine) methylase will decrease, increase or will have no effect on the mutation rates should be explained.

Concept introduction:

Deoxyadenosine methylase is commonly referred to as DAM methylase. This is an enzyme that catalyzes the addition of methyl ( CH3 ) group to the adenine of the sequence of 5'−GATC−3' in the DNA (Deoxyribonucleic acid) which is newly synthesized.

Expert Solution & Answer

Explanation of Solution

The process of addition of methyl group to the adenine of the sequence of 5'−GATC−3' in the DNA can be referred to as DNA methylation. The process of DNA methylation stabilizes the newly synthesized DNA as well as help in the development of embryo and cell differentiation.

During the process of replication, methylated DNA strand remains temporarily unmethylated. Thus, in the two strands of DNA, one strand of DNA remains methylated, while the other strand of DNA remains unmethylated. This situation is referred to as hem-methylation. The unmethylated strand of DNA quickly methylates in the presence of enzyme dam methylase.

In the deficiency of enzyme dam methylase, DNA is left completely unmethylated. Also, the unmethylated DNA has more probability to undergo mutation. Thus, the deficiency of dam methylase enzyme increases the spontaneous mutation rates.

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Students have asked these similar questions

Draw a diagram to demonstrate 3' to 5' exonuclease activity?

1. Write the piece of mRNA that would code for the amino acid sequence NH3 - met - tyr - cys- his- CO2. Label the 5' and 3' ends. (diagram attached) 2.

You were tasked with purifying an untagged transcription factor (molecular weight 65,000Da, isoelectric point unknown) from a contaminant Protein A (molecular weight 50,000 Da, isoelectric point 5.0). You were also instructed to use the protein for crystallization studies after purification.i) In the initial purification step, which type of chromatography should you attempt? Explain your choice and specify the requirements of the buffer solution you should use. ii) Analyzing the proteins recovered from step i) using SDS-PAGE, you still observed a faint band of Protein A in addition to the transcription factor band. Given the limited time available for further purification, you must choose ONE appropriate chromatography method to maximize the chances of separating the two proteins as well as your crystallization studies. Provide a detailed explanation of your selection and the techniques/strategies you would employ to achieve this.

Answer 2

Question

Chapter 23, Problem 1P

Interpretation Introduction

Interpretation:

If the deficiency of DAM (deoxyadenosine) methylase will decrease, increase or will have no effect on the mutation rates should be explained.

Concept introduction:

Deoxyadenosine methylase is commonly referred to as DAM methylase. This is an enzyme that catalyzes the addition of methyl ( CH3 ) group to the adenine of the sequence of 5'−GATC−3' in the DNA (Deoxyribonucleic acid) which is newly synthesized.

Expert Solution & Answer

Explanation of Solution

The process of addition of methyl group to the adenine of the sequence of 5'−GATC−3' in the DNA can be referred to as DNA methylation. The process of DNA methylation stabilizes the newly synthesized DNA as well as help in the development of embryo and cell differentiation.

During the process of replication, methylated DNA strand remains temporarily unmethylated. Thus, in the two strands of DNA, one strand of DNA remains methylated, while the other strand of DNA remains unmethylated. This situation is referred to as hem-methylation. The unmethylated strand of DNA quickly methylates in the presence of enzyme dam methylase.

In the deficiency of enzyme dam methylase, DNA is left completely unmethylated. Also, the unmethylated DNA has more probability to undergo mutation. Thus, the deficiency of dam methylase enzyme increases the spontaneous mutation rates.

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Answer 3

Question

Chapter 23, Problem 1P

Interpretation Introduction

Interpretation:

If the deficiency of DAM (deoxyadenosine) methylase will decrease, increase or will have no effect on the mutation rates should be explained.

Concept introduction:

Deoxyadenosine methylase is commonly referred to as DAM methylase. This is an enzyme that catalyzes the addition of methyl ( CH3 ) group to the adenine of the sequence of 5'−GATC−3' in the DNA (Deoxyribonucleic acid) which is newly synthesized.

Expert Solution & Answer

Explanation of Solution

The process of addition of methyl group to the adenine of the sequence of 5'−GATC−3' in the DNA can be referred to as DNA methylation. The process of DNA methylation stabilizes the newly synthesized DNA as well as help in the development of embryo and cell differentiation.

During the process of replication, methylated DNA strand remains temporarily unmethylated. Thus, in the two strands of DNA, one strand of DNA remains methylated, while the other strand of DNA remains unmethylated. This situation is referred to as hem-methylation. The unmethylated strand of DNA quickly methylates in the presence of enzyme dam methylase.

In the deficiency of enzyme dam methylase, DNA is left completely unmethylated. Also, the unmethylated DNA has more probability to undergo mutation. Thus, the deficiency of dam methylase enzyme increases the spontaneous mutation rates.

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Answer 4

Question

Chapter 23, Problem 1P

Interpretation Introduction

Interpretation:

If the deficiency of DAM (deoxyadenosine) methylase will decrease, increase or will have no effect on the mutation rates should be explained.

Concept introduction:

Deoxyadenosine methylase is commonly referred to as DAM methylase. This is an enzyme that catalyzes the addition of methyl ( CH3 ) group to the adenine of the sequence of 5'−GATC−3' in the DNA (Deoxyribonucleic acid) which is newly synthesized.

Expert Solution & Answer

Explanation of Solution

The process of addition of methyl group to the adenine of the sequence of 5'−GATC−3' in the DNA can be referred to as DNA methylation. The process of DNA methylation stabilizes the newly synthesized DNA as well as help in the development of embryo and cell differentiation.

During the process of replication, methylated DNA strand remains temporarily unmethylated. Thus, in the two strands of DNA, one strand of DNA remains methylated, while the other strand of DNA remains unmethylated. This situation is referred to as hem-methylation. The unmethylated strand of DNA quickly methylates in the presence of enzyme dam methylase.

In the deficiency of enzyme dam methylase, DNA is left completely unmethylated. Also, the unmethylated DNA has more probability to undergo mutation. Thus, the deficiency of dam methylase enzyme increases the spontaneous mutation rates.

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Answer 5

Chapter 23, Problem 1P

Interpretation Introduction

Interpretation:

If the deficiency of DAM (deoxyadenosine) methylase will decrease, increase or will have no effect on the mutation rates should be explained.

Concept introduction:

Deoxyadenosine methylase is commonly referred to as DAM methylase. This is an enzyme that catalyzes the addition of methyl ( CH3 ) group to the adenine of the sequence of 5'−GATC−3' in the DNA (Deoxyribonucleic acid) which is newly synthesized.

Expert Solution & Answer

Explanation of Solution

The process of addition of methyl group to the adenine of the sequence of 5'−GATC−3' in the DNA can be referred to as DNA methylation. The process of DNA methylation stabilizes the newly synthesized DNA as well as help in the development of embryo and cell differentiation.

During the process of replication, methylated DNA strand remains temporarily unmethylated. Thus, in the two strands of DNA, one strand of DNA remains methylated, while the other strand of DNA remains unmethylated. This situation is referred to as hem-methylation. The unmethylated strand of DNA quickly methylates in the presence of enzyme dam methylase.

In the deficiency of enzyme dam methylase, DNA is left completely unmethylated. Also, the unmethylated DNA has more probability to undergo mutation. Thus, the deficiency of dam methylase enzyme increases the spontaneous mutation rates.

Answer 6

Chapter 23, Problem 1P

Interpretation Introduction

Interpretation:

If the deficiency of DAM (deoxyadenosine) methylase will decrease, increase or will have no effect on the mutation rates should be explained.

Concept introduction:

Deoxyadenosine methylase is commonly referred to as DAM methylase. This is an enzyme that catalyzes the addition of methyl ( CH3 ) group to the adenine of the sequence of 5'−GATC−3' in the DNA (Deoxyribonucleic acid) which is newly synthesized.

Expert Solution & Answer

Explanation of Solution

The process of addition of methyl group to the adenine of the sequence of 5'−GATC−3' in the DNA can be referred to as DNA methylation. The process of DNA methylation stabilizes the newly synthesized DNA as well as help in the development of embryo and cell differentiation.

During the process of replication, methylated DNA strand remains temporarily unmethylated. Thus, in the two strands of DNA, one strand of DNA remains methylated, while the other strand of DNA remains unmethylated. This situation is referred to as hem-methylation. The unmethylated strand of DNA quickly methylates in the presence of enzyme dam methylase.

In the deficiency of enzyme dam methylase, DNA is left completely unmethylated. Also, the unmethylated DNA has more probability to undergo mutation. Thus, the deficiency of dam methylase enzyme increases the spontaneous mutation rates.

Answer 7

Chapter 23, Problem 1P

Interpretation Introduction

Interpretation:

If the deficiency of DAM (deoxyadenosine) methylase will decrease, increase or will have no effect on the mutation rates should be explained.

Concept introduction:

Deoxyadenosine methylase is commonly referred to as DAM methylase. This is an enzyme that catalyzes the addition of methyl ( CH3 ) group to the adenine of the sequence of 5'−GATC−3' in the DNA (Deoxyribonucleic acid) which is newly synthesized.

Answer 8

Expert Solution & Answer

Explanation of Solution

The process of addition of methyl group to the adenine of the sequence of 5'−GATC−3' in the DNA can be referred to as DNA methylation. The process of DNA methylation stabilizes the newly synthesized DNA as well as help in the development of embryo and cell differentiation.

During the process of replication, methylated DNA strand remains temporarily unmethylated. Thus, in the two strands of DNA, one strand of DNA remains methylated, while the other strand of DNA remains unmethylated. This situation is referred to as hem-methylation. The unmethylated strand of DNA quickly methylates in the presence of enzyme dam methylase.

In the deficiency of enzyme dam methylase, DNA is left completely unmethylated. Also, the unmethylated DNA has more probability to undergo mutation. Thus, the deficiency of dam methylase enzyme increases the spontaneous mutation rates.