Microbiology: An Introduction, Books a la Carte Plus Mastering Microbiology with Pearson eText -- Access Card Package (13th Edition)
Microbiology: An Introduction, Books a la Carte Plus Mastering Microbiology with Pearson eText -- Access Card Package (13th Edition)
13th Edition
ISBN: 9780134729336
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case, Derek Weber, Warner Bair
Publisher: PEARSON
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Chapter 23, Problem 1A
Summary Introduction

Introduction:

Toxoplama gondii is a eukaryotic obligate intracellular parasite belongs to phylum  Apicomplexa,  genus Toxoplama  species gondii causes  toxoplasmosis. Disease associated  are  neurological disorder like  schizophrenia  and bipolar disorder. It causes serious  infections in immunosuppresant, infants,  HIV/AIDS patients  which ultimately leads to death.

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You aim to test the hypothesis that the Tbx4 and Tbx5 genes inhibit each other's expression during limb development. With access to chicken embryos and viruses capable of overexpressing Tbx4 and Tbx5, describe an experiment to investigate whether these genes suppress each other's expression in the limb buds. What results would you expect if they do repress each other? What results would you expect if they do not repress each other?
You decide to delete Fgf4 and Fgf8 specifically in the limb bud. Explain why you would not knock out these genes in the entire embryo instead.
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