Biochemistry 410/411 Textbook - 5th Edition - Custom Texas A&M University
5th Edition
ISBN: 9781119302940
Author: Voet
Publisher: WILEY C
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Chapter 23, Problem 13E
Summary Introduction
To explain: The reason why methotrexate inhibits the synthesis of histidine and methionine.
Concept introduction: Competitive inhibition is the competition between a substrate and inhibitor that compete for the same active site of enzyme. The compound which resembles the substrate can act as competitive inhibitor.
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For a red blood cell (erythrocyte) undergoing active glycolysis, briefly explain how
increases in concentration of the following factors are likely to affect glycolytic flux.
a. ATP
b. AMP
c. F-1,6-BP
d. F-2,6-BP
e. Citrate
f. Glucose-6-phosphate
The ∆G°’ for hydrolysis of phosphoenol pyruvate is -62.2 kJ/mol. The standard freeenergy of ATP hydrolysis is -30.5 kJ/mol.
A. What is the standard free energy and K eq of the spontaneous reaction betweenADP/ATP and phosphoenol pyruvate.
B. Repeat A for F-1,6-BP (∆G°’=-16.7 kJ/mol) and 1,3-BPG (∆G°’=-49.6 kJ/mol)hydrolysis.
C. If the ATP and ADP concentrations are 8mM and 1mM respectively, what would bethe ratio of pyruvate/phosphoenolpyruvate at equilibrium?
Answer
Chapter 23 Solutions
Biochemistry 410/411 Textbook - 5th Edition - Custom Texas A&M University
Ch. 23 - Prob. 1ECh. 23 - Prob. 2ECh. 23 - Prob. 3ECh. 23 - 4. When starved, bacteria produce the...Ch. 23 - Prob. 5ECh. 23 - Prob. 6ECh. 23 - 7. Calculate the cost, in ATP equivalents, of...Ch. 23 - Prob. 8ECh. 23 - Prob. 9ECh. 23 - Prob. 10E
Ch. 23 - Prob. 11ECh. 23 - Prob. 12ECh. 23 - Prob. 13ECh. 23 - Prob. 14ECh. 23 - Prob. 15ECh. 23 - Prob. 16ECh. 23 - Prob. 17ECh. 23 - Prob. 18ECh. 23 - Prob. 19ECh. 23 - Prob. 20ECh. 23 - Prob. 22ECh. 23 - Prob. 21ECh. 23 - Prob. 23ECh. 23 - Prob. 24ECh. 23 - Prob. 25CQCh. 23 - Prob. 26CQCh. 23 - Prob. 27CQCh. 23 - Prob. 28CQCh. 23 - Prob. 29CQCh. 23 - Prob. 30CQCh. 23 - 31. Why is gout more prevalent in populations that...Ch. 23 - Prob. 32CQCh. 23 - Prob. 33CQCh. 23 - Prob. 34CQCh. 23 - Prob. 1MTE
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