EBK BIOCHEMISTRY
6th Edition
ISBN: 9781337431200
Author: GRISHAM
Publisher: CENGAGE LEARNING - CONSIGNMENT
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Question
Chapter 23, Problem 10P
Interpretation Introduction
Interpretation:
The consequences of a carnitine deficiency for fatty acid oxidation should be discussed.
Concept Introduction:
Most of the enzymes of ß oxidation pathway are in the mitochondrial matrix. Short chain fatty acids are transported to the matrix as free acids and convert to acyl CoA derivatives. Long chain fatty acids cannot be transported to the matrix directly. Therefore, they must be converted to acylcarnitine derivatives. Carnitine acyltransferase I is associated with the outer mitochondrial membrane. It catalyzes the formation of O-acylcarnitine. This is transported across the inner mitochondrial membrane by translocase. Then acylcarnitine is transferred to carnitine acyltransferase II on matrix side. This enzyme transfers fatty acyl group back to CoA leaving free carnitine which can return across the membrane via translocase.
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Students have asked these similar questions
9. Which one of the compounds below is the major organic product obtained from
the following reaction sequence, starting with ethyl acetoacetate?
요요.
1. NaOCH2CH3
CH3CH2OH
1. NaOH, H₂O
2. H3O+
3. A
OCH2CH3
2.
ethyl acetoacetate
ii
A
3. H3O+
OH
B
C
D
E
7. Only one of the following ketones cannot be made via an acetoacetic ester
synthesis. Which one is it?
Ph
کہ
A
B
C
D
E
2. Which one is the
major organic
product obtained
from the following
reaction sequence?
HO
A
OH
1. NaOEt, EtOH
1. LiAlH4
EtO
OEt
2. H3O+
2. H3O+
OH
B
OH
OH
C
-OH
HO
-OH
OH
D
E
.CO₂Et
Chapter 23 Solutions
EBK BIOCHEMISTRY
Ch. 23 - Prob. 1PCh. 23 - Determining the Amount of ATP Produced from Fatty...Ch. 23 - Prob. 3PCh. 23 - Examining the Labeling of Glucose from 14C.labeled...Ch. 23 - Prob. 5PCh. 23 - Prob. 6PCh. 23 - Prob. 7PCh. 23 - Prob. 8PCh. 23 - Prob. 9PCh. 23 - Prob. 10P
Ch. 23 - Prob. 11PCh. 23 - Understanding Human Energy Consumption During...Ch. 23 - Prob. 13PCh. 23 - Prob. 14PCh. 23 - Prob. 15PCh. 23 - Extending the Mechanism of Methylmalonyl-CoA...Ch. 23 - Prob. 17PCh. 23 - Prob. 18PCh. 23 - Prob. 19PCh. 23 - Understanding a Ubiquitous Series of Metabolic...Ch. 23 - Using the ActiveModel for enoyl-CoA dehydratase,...
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