The reagents a-c missing in the reaction sequence given are to be identified. Concept introduction: Alkylation of β- keto esters can be carried out by treating its enolate anion with alkyl halides. β-Keto esters give upon hydrolysis a β- keto acid which decarboxylates on heating. Direct alkylation at α- carbon is possible by treating with LDA and alkyl halides.

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Answer 1

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Chapter 22.SE, Problem 54AP

Interpretation Introduction

Interpretation:

The reagents a-c missing in the reaction sequence given are to be identified.

Concept introduction:

Alkylation of β- keto esters can be carried out by treating its enolate anion with alkyl halides. β-Keto esters give upon hydrolysis a β- keto acid which decarboxylates on heating. Direct alkylation at α- carbon is possible by treating with LDA and alkyl halides.

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Answer 2

Question

Chapter 22.SE, Problem 54AP

Interpretation Introduction

Interpretation:

The reagents a-c missing in the reaction sequence given are to be identified.

Concept introduction:

Alkylation of β- keto esters can be carried out by treating its enolate anion with alkyl halides. β-Keto esters give upon hydrolysis a β- keto acid which decarboxylates on heating. Direct alkylation at α- carbon is possible by treating with LDA and alkyl halides.

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Answer 3

Question

Chapter 22.SE, Problem 54AP

Interpretation Introduction

Interpretation:

The reagents a-c missing in the reaction sequence given are to be identified.

Concept introduction:

Alkylation of β- keto esters can be carried out by treating its enolate anion with alkyl halides. β-Keto esters give upon hydrolysis a β- keto acid which decarboxylates on heating. Direct alkylation at α- carbon is possible by treating with LDA and alkyl halides.

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Answer 4

Question

Chapter 22.SE, Problem 54AP

Interpretation Introduction

Interpretation:

The reagents a-c missing in the reaction sequence given are to be identified.

Concept introduction:

Alkylation of β- keto esters can be carried out by treating its enolate anion with alkyl halides. β-Keto esters give upon hydrolysis a β- keto acid which decarboxylates on heating. Direct alkylation at α- carbon is possible by treating with LDA and alkyl halides.

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Answer 5

Chapter 22.SE, Problem 54AP

Interpretation Introduction

Interpretation:

The reagents a-c missing in the reaction sequence given are to be identified.

Concept introduction:

Alkylation of β- keto esters can be carried out by treating its enolate anion with alkyl halides. β-Keto esters give upon hydrolysis a β- keto acid which decarboxylates on heating. Direct alkylation at α- carbon is possible by treating with LDA and alkyl halides.

Answer 6

Chapter 22.SE, Problem 54AP

Interpretation Introduction

Interpretation:

The reagents a-c missing in the reaction sequence given are to be identified.

Concept introduction:

Alkylation of β- keto esters can be carried out by treating its enolate anion with alkyl halides. β-Keto esters give upon hydrolysis a β- keto acid which decarboxylates on heating. Direct alkylation at α- carbon is possible by treating with LDA and alkyl halides.

Answer 7

Chapter 22.SE, Problem 54AP

Interpretation Introduction

Interpretation:

The reagents a-c missing in the reaction sequence given are to be identified.

Concept introduction:

Alkylation of β- keto esters can be carried out by treating its enolate anion with alkyl halides. β-Keto esters give upon hydrolysis a β- keto acid which decarboxylates on heating. Direct alkylation at α- carbon is possible by treating with LDA and alkyl halides.

Answer 8

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Answer 9

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Answer 10

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Answer 11

Ch. 22.1 - Prob. 1P Ch. 22.1 - How many acidic hydrogens does each of the...Ch. 22.1 - Prob. 3P Ch. 22.3 - Write the complete mechanism for the deuteration...Ch. 22.3 - Prob. 5P Ch. 22.4 - If methanol rather than water is added at the end...Ch. 22.5 - Prob. 7P Ch. 22.5 - Draw a resonance structure of the acetonitrile...Ch. 22.6 - If methanol rather than water is added at the end...Ch. 22.7 - Prob. 10P

Solution Summary: The author explains that the reagents a-c missing in the reaction sequence are to be identified.

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Chapter 22 Solutions